OVA Conjugated Cytokeratin Fragment Antigen 21-1 (CYFRA21-1)

Source

Protein conjugation
Predicted Molecular Mass KD

NA
Accurate Molecular Mass KD

NA
Organism species

Homo sapiens (Human)
Item Name

Cytokeratin Fragment Antigen 21-1
Alternative Names

NA
Research Area

NA
Buffer Formulation

PBS, pH7.4.
Traits

Freeze-dried powder
Purity

>90%
Protein length

NA
Tag

No tag
Expression System

Protein Conjugation
Application

Immunogen; SDS-PAGE; WB
Manual link
Description

Antigens are peptides or recombinant or native dependent on the production method.
Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

Gene target

OVA Conjugated Cytokeratin 21-1 CYFRA21-1
Gene symbol

TRC-GCA21-1, TRSUP-TTA2-1, TRA-AGC21-1, TRN-GTT21-1, TRL-CAG2-1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1
Short name

OVA Conjugated Cytokeratin Antigen 21-1 (CYFRA21-1)
Technique

antigen, antigenes, antibody Conjugates
Host

chemical synthesis
Isotype

Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
Species

Homo sapiens (Human)
Alternative name

OVA coupled Cytokeratin Fragment protein 21-1 (CYFRA21-1)
Alternative technique

antigenes

Identity

HGNC:34943
Gene

TRC-GCA21-1
Long gene name

tRNA-Cys (anticodon GCA) 21-1
Synonyms gene
- TRNAC25
Synonyms gene name
- transfer RNA cysteine 25 (anticodon GCA)
- transfer RNA-Cys (GCA) 21-1
Synonyms
- tRNA-Cys-GCA-21-1
GenBank acession
- HG983711
Locus

7q36.1
Discovery year

2008-08-29
Entrez gene record

100189375
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:34897
Gene

TRSUP-TTA2-1
Long gene name

tRNA suppressor (anticodon TTA) 2-1
Synonyms gene
- TRNASUP2
Synonyms gene name
- transfer RNA suppressor 2 (anticodon UUA)
- transfer RNA suppressor (TTA) 2-1
Synonyms
- tRNA-Sup-TTA-2-1
GenBank acession
- HG984040
Locus

21
Discovery year

2008-08-29
Entrez gene record

100189330

Identity

HGNC:34755
Gene

TRA-AGC21-1
Long gene name

tRNA-Ala (AGC) 21-1
Synonyms gene
- TRNAA21
Synonyms gene name
- transfer RNA alanine 21 (anticodon AGC)
- transfer RNA-Ala (AGC) 21-1
Synonyms
- tRNA-Ala-AGC-21-1
GenBank acession
- HG983575
Locus

6p22.2
Discovery year

2008-08-29
Entrez gene record

100189192
Classification
- Low confidence cytoplasmic transfer RNAs

Identity

HGNC:38584
Gene

TRN-GTT21-1
Long gene name

tRNA-Asn (anticodon GTT) 21-1
Synonyms gene
- TRNAN38
Synonyms gene name
- transfer RNA asparagine 38 (anticodon GUU)
- transfer RNA-Asn (GTT) 21-1
Synonyms
- tRNA-Asn-GTT-21-1
GenBank acession
- HG983661
Locus

1q21.2
Discovery year

2010-06-23
Entrez gene record

100873961
Classification
- Cytoplasmic transfer RNA pseudogenes

Identity

HGNC:34692
Gene

TRL-CAG2-1
Long gene name

tRNA-Leu (anticodon CAG) 2-1
Synonyms gene
- TRNAL13
Synonyms gene name
- transfer RNA leucine 13 (anticodon CAG)
- transfer RNA-Leu (CAG) 2-1
Synonyms
- tRNA-Leu-CAG-2-1
GenBank acession
- HG983896
Locus

16q13-21
Discovery year

2008-08-29
Entrez gene record

100189130
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data