CD18, Activation Epitope (Leukocyte Function Associated Antigen, LFA-1 beta2) (Biotin) Antibody

• Catalog number
  GEN601133
• Price
  Please ask
• Size
  100ug

• Also known as
  CD18, Activation Epitope
• Other names
  CD18; N/A; CD18; N/A; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  LOC100304487; N/A; N/A; N/A
• Gene name synonims
  LOC100304487; N/A; N/A; N/A
• Other gene names
  LOC100304487; N/A; N/A; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  3H1050
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone 3H1050 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by 3H1050 is also exposed during dissociation of the CD11/CD18 by low pH.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Purified IgG conjugated to Biot- liquid with 0.1% sodium azide, 1% BSA.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at -20 degrees Celsius.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Description
  Antigens are peptides or recombinant or native dependent on the production method.
• Conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  CD18   Activation   Epitope   Leukocyte   Associated   LFA-1   beta2  
• Gene symbol
  ITGB2, ITGAL, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
• Short name
  CD18, Activation Epitope (Leukocyte Associated Antigen, LFA-1 beta2) ( ) Antibody
• Technique
  activation, Antibody, antigen, antibodies against human proteins, antibodies for, antigenes
• Label
  Biotin
• Alternative name
  Anti-CD18, Activation Epitope (Leukocyte Function Associated Antigen, LFA-1 beta2) (Biotin)
• Alternative technique
  antibodies, antigenes

Gene info

• Identity
  HGNC:6155
• Gene
  ITGB2
• Long gene name
  integrin subunit beta 2
• Synonyms gene
  • CD18
  • MFI7
• Synonyms gene name
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
• Synonyms
  • LFA-1
  • MAC-1
• Synonyms name
  • complement component 3 receptor 3 and 4 subunit
• GenBank acession
  • AK222505
• Locus
  21q22.3
• Discovery year
  1986-01-01
• Entrez gene record
  3689
• RefSeq identity
  • NM_000211
• Classification
  • Integrin beta subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000090257
• Locus Specific Databases
  • ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
  • LRG_76

Gene info

• Identity
  HGNC:6148
• Gene
  ITGAL
• Long gene name
  integrin subunit alpha L
• Synonyms gene
  • CD11A
• Synonyms gene name
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
• Synonyms
  • LFA-1
  • LFA1A
• Synonyms name
  • antigen CD11A (p180)
  • lymphocyte function-associated antigen 1, alpha polypeptide
• Locus
  16p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  3683
• Pubmed identfication
  • 3284962
• Classification
  • Integrin alpha subunits
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000176964

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

Gene info

• Identity
  HGNC:31545
• Gene
  MIR16-1
• Long gene name
  microRNA 16-1
• Synonyms gene
  • MIRN16-1
• Synonyms
  • hsa-mir-16-1
• Locus
  13q14.2
• Discovery year
  2004-04-23
• Entrez gene record
  406950
• RefSeq identity
  • NR_029486
• Classification
  • MicroRNA MIR15/16 family

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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