Human CellExp™ SARS-CoV-2 S1 Protein (D614G), Recombinant

  • Catalog number
    P1652-50
  • Price
    Please ask
  • Size
    50 µg
  • Synonyms
    SARS-CoV-2 S1 Protein (D614G), Recombinant,SARS-CoV-2 S1 Protein (D614G),SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G), Recombinant,S1 Protein (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 Protein (D614G),S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G)
  • Alternative_names
    SARS-CoV-2 S1 Protein (D614G), Recombinant,SARS-CoV-2 S1 Protein (D614G),SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G), Recombinant,S1 Protein (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G),Human CellExp™ SARS-CoV-2 S1 Protein (D614G),S1 (D614G),Human CellExp™ SARS-CoV-2 S1 (D614G)
  • Description
    Recombinant SARS-CoV-2 S1 spike protein with a mutation (D614G)
  • Recombinant
    1
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
    > 95% SDS-PAGE
  • Molecular Weight
    120 kDa
  • Storage Temp
    -20ºC
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Concentration
    Lot dependent
  • Appearance
    Lyophilized powder
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
  • Background Information
    SARS-CoV-2, the causative virus of COVID-19, uses the viral Spike (S) protein for host cell attachment and entry. The virus uses multiple factors including the human protease Furin, Angiotensin converting enzyme 2 (ACE2), Neuropilin-1 (NRP1) and the transmembrane protease serine 2 (TMPRSS2) for receptor interactions. The S protein has two domains S1 and S2, where S1 facilitates initial binding to the receptor and the S2 domain drives the membrane fusion and eventual entry of the virus. The S glycoprotein serves as an important target for monoclonal antibodies, entry inhibitors, and vaccines. Within the S1 protein, the conserved receptor-binding domain (RBD) binds with a high affinity for ACE2. Recently, a new strain of SARS-CoV-2 has been discovered with a mutation in the S1 protein (amino acid D614 to G614) outside the RBD. Early studies provide evidence that D614G SARS-CoV-2 virus strain is likely to be more infectious and is present in the majority of current infections globally.
  • Amino acid sequence
    Val 16 - Arg 685
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    SARS1, SARS2
  • Short name
    CellExp™ SARS-CoV-2 S1 Protein (D614G), Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ SARS-CoV-2 S1 Protein (D614G), Rec.
  • Alternative technique
    rec
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee