Ro 20-1724, PDE4 inhibitor
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Catalog numberSIH-527-250MG
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PricePlease ask
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Size250 mg
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Stock availabilitIn StockIn Stock
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CAS number29925-17-5
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DescriptionPDE4 inhibitor
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Molecular weight278,3 g/mol
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Primary research fieldsCell signaling
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Other nameB8279, 4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, Ro 20 1724, RO 20-1724, 4-(3-butoxy-4-methoxy-benzyl)imidazolidin-2-one
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Product categorySmall Molecules
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Product typeInhibitor
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Chemical formulaC15H22N2O3
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OriginSynthetic
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Purity pourcentage>98% (TLC); NMR (Conforms)
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Soluble inSoluble in DMSO (200 mg/ml) or ethanol (40 mg/ml)
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Physical appearanceWhite powder
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Storage recommendations-20ºC
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Shipping recommendationsShipped Ambient
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Safety informationClassification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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PubChem number5087
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Scientific contextSee included datasheet or contact our support service
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BibliographyRefer to NCBI PubMed
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Release date30/Aug/2016
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Representative figure legendChemical structure of Ro 20-1724 (SIH-527), a PDE4 inhibitor. CAS #: 29925-17-5. Molecular Formula: C15H22N2O3. Molecular Weight: 278.3 g/mol. Chemical structure of Ro 20-1724, a PDE4 inhibitor (SIH-527). CAS # 29925-17-5. Molecular Formula: C15H22N2O3.
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg0.25
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Net weight g0.25
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolPIRC103, SNORD114-20, SNORD116-20, IGLVI-20, PIRC104, IGHV3-20, SNORD115-20
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Short nameRo 20-1724, PDE4 inhibitor
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Alternative nameRo 20-1724, PDE4 suppressor
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Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 103
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-20
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-20
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable (I)-20 (pseudogene)
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Synonyms gene name
- immunoglobulin lambda variable (I)-20
- immunoglobulin lambda variable (I)-20 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 104
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-20
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-20
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box