PD-169316

• Catalog number
  P217600
• Price
  Please ask
• Size
  10 mg

• Chemical available in other sizes
  Please inquire size and price
• Stock availability
  Please Inquire
• Cas number
  152121-53-4
• Chemical s molecular weight
  360.34
• Chemical s main applications
  PD 169316 is a highly selective, potent inhibitor of p38 MAP kinase. PD 169316 inhibits transforming growth factor β-induced Smad signaling in human ovarian cancer cells. PD 169316 acts as an an endogenous suppressor of apoptosis by mimicking CD9, a membrane tetraspanin. Studies show that PD 169316 reduces myocardial ischemia/reperfusion induced voltage-dependent anion channel(VDAC) phosphorylation
• Chemical s category
  Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
• Other name
  4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine; 4-[5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl]pyridine;
• Chemical s formula
  C20H13FN4O2
• Physical properties
  No Data Available
• Melting temperature
  No Data Available
• Boiling temperature
  No Data Available
• Chemical s soluble in
  No Data Available
• Stability conditions
  No Data Available
• Storage
  No Data Available
• Chemical s specifications

• Gene target
  PD-169316  
• Gene symbol
  ENPP2, PDCD1, ENPP3, PDCD1LG2, CD274, VSIR
• Short name
  PD-169316
• Alternative name
  PD-169316

Gene info

• Identity
  HGNC:3357
• Gene
  ENPP2
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 2
• Synonyms gene
  • PDNP2
• Synonyms
  • ATX
  • PD-IALPHA
• Synonyms name
  • autotaxin
• GenBank acession
  • D45421
• Locus
  8q24.12
• Discovery year
  1995-08-10
• Entrez gene record
  5168
• Pubmed identfication
  • 8586446
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000164995

Gene info

• Identity
  HGNC:8760
• Gene
  PDCD1
• Long gene name
  programmed cell death 1
• Synonyms gene
  • SLEB2
• Synonyms gene name
  • systemic lupus erythematosus susceptibility 2
• Synonyms
  • CD279
  • PD1
  • hSLE1
  • PD-1
• GenBank acession
  • AY206416
• Locus
  2q37.3
• Discovery year
  1994-05-24
• Entrez gene record
  5133
• Pubmed identfication
  • 7851902
  • 12402038
• RefSeq identity
  • NM_005018
• Classification
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000151342

Gene info

• Identity
  HGNC:3358
• Gene
  ENPP3
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 3
• Synonyms gene
  • PDNP3
• Synonyms
  • PD-IBETA
  • gp130RB13-6
  • B10
  • CD203c
• GenBank acession
  • AF005632
• Locus
  6q23.2
• Discovery year
  1995-08-10
• Entrez gene record
  5169
• Pubmed identfication
  • 9344668
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
  • CD molecules
• VEGA ID
  OTTHUMG00000016292

Gene info

• Identity
  HGNC:18731
• Gene
  PDCD1LG2
• Long gene name
  programmed cell death 1 ligand 2
• Synonyms
  • PD-L2
  • Btdc
  • PDL2
  • bA574F11.2
  • CD273
  • B7-DC
• Synonyms name
  • B7 dendritic cell molecule
• GenBank acession
  • AF344424
• Locus
  9p24.1
• Discovery year
  2003-11-14
• Entrez gene record
  80380
• Pubmed identfication
  • 11224527
• RefSeq identity
  • NM_025239
• Classification
  • B7 family
  • CD molecules
  • Immunoglobulin like domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000019504

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Similar products