Clonality Polyclonal Antibody
Other name Anti-AANAT (Thr29) Polyclonal
Host organism Rabbit (Oryctolagus cuniculus)
Background information Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle.
Also known as AANAT (Thr29) Polyclonal Antibody
Swiss Prot N/A
Specificity This antibody reacts specifically with AANAT (Thr29)
Modification site Thr29
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Conjugated with ALEXA FLUOR® 594
Gene ID 11298
Clone Polyclonal Antibodies
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Synonyms p-AANATThr29; p-AANATT29; AANATphospho Thr29; p-AANATT29
Subcellular locations N/A
Concentration 1ug per 1ul
Purification method Purified by Protein A.
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Type Conjugated Primary Antibody
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Excitation emission 590nm/617nm
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target Protein/Peptide AANAT Thr29
Antigen Source KLH conjugated synthetic phosphopeptide derived from mouse AANAT around the phosphorylation site of Thr29
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Short name Anti-AANAT (Thr29) (Polyclonal)
Technique Polyclonal, anti
Label ALEXA FLUOR 594
Alternative name antibody to-aralkylamine N-acetyltransferase (Thr29) (polyclonal), ALEXA Fluor 594
Alternative technique polyclonals
Alternative to gene target aralkylamine N-acetyltransferase, DSPS and SNAT, AANAT and IDBG-69711 and ENSG00000129673 and 15, 14-3-3 protein binding, Cytoplasm, Aanat and IDBG-214486 and ENSMUSG00000020804 and 11298