Angiostatin Human

• Catalog number
  4919-500
• Price
  Please ask
• Size
  500 ug

• Synonyms
  Angiostatin K1-4, Angiostatin Kringles 1-4
• Alternative_names
  Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen
• Description
  An endogenous angiogenesis inhibitor
• Recombinant
  No
• Source
  Human Plasma
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Molecular Weight
  50.0 kDa
• Storage Temp
  -80°C
• Shipping
  Dry ice
• Shelf Life
  12 months
• Concentration
  7.0-8.0 mg/ml
• Appearance
  Liquid
• Physical form description
  In 20 mM HEPES, 150 mM NaCl, pH 7.4
• Background Information
  Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1 - 4. It is a potent angiogenesis inhibitor and the inhibition of angiogenesis by angiostatin is directly related to inhibiting the proliferation of endothelial cells. Human Angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM – 1.0 µM.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Angiostatin  
• Short name
  Angiostatin
• Species
  Human, Humans
• Alternative name
  Angiostatin H. sapiens

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