Histone H2B (1-123 aa), Xenopus recombinant
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Catalog number
7669-100
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Price
Please ask
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Size
100 ug
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Synonyms
Histone H2B (1-123 aa), Xenopus recombinant
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Alternative_names
H2B, Histone H2B type 1-A, HIST1H2BA, TSH2B
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Description
Core component of nucleosome
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥90%
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Assay
SDS-PAGE
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Molecular Weight
13.7 kDa (1-123 aa)
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Storage Temp
-80°C
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Shipping
dry ice
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Shelf Life
6 months
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Appearance
Lyophilized powder
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Physical form description
Lyophilized powder. Recommended buffer is 50 mM sodium phosphate, pH 7.2, containing 300 mM sodium chloride, 1 mM DTT, 1 mM EDTA and 20% glycerol.
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Background Information
H2A is a core component of nucleosome. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones. The octamer is composed of two of each histone H2A, H2B, H3, and H4. DNA accessibility is regulated via a complex set of post-translational modifications of these histones, also called histone code, and nucleosome remodeling. Histones H2A and H2B form a dimer. Histones H3 and H4 form a tetramer. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H2B undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, sumoylation, and biotinylation that are important for regulation of gene transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
H2BC21, H2BC4, H2BC8, H2BC17, H2BC19P, H2BC20P, RNF11, H2BC7, H2BC3, H2BC11
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Short name
Histone H2B (1-123 aa), Xenopus recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Xenopus, Xenopuses
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Alternative name
Histone H2B (1-123 aa), Xenopus Rec.
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 21
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Synonyms gene
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Synonyms gene name
- H2B histone family, member Q
- histone 2, H2be
- histone cluster 2, H2be
- histone cluster 2 H2B family member e
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 4
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Synonyms gene
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Synonyms gene name
- H2B histone family, member L
- histone 1, H2bc
- histone cluster 1, H2bc
- histone cluster 1 H2B family member c
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 8
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Synonyms gene
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Synonyms gene name
- H2B histone family, member A
- histone 1, H2bg
- histone cluster 1, H2bg
- histone cluster 1 H2B family member g
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 17
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Synonyms gene
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Synonyms gene name
- H2B histone family, member N
- histone 1, H2bo
- histone cluster 1, H2bo
- histone cluster 1 H2B family member o
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
ring finger protein 11
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-01-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 7
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Synonyms gene
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Synonyms gene name
- H2B histone family, member G
- histone 1, H2bf
- histone cluster 1, H2bf
- histone cluster 1 H2B family member f
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 3
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Synonyms gene
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Synonyms gene name
- H2B histone family, member F
- histone 1, H2bb
- histone cluster 1, H2bb
- histone cluster 1 H2B family member b
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Synonyms
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GenBank acession
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Locus
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Discovery year
1997-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
H2B clustered histone 11
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Synonyms gene
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Synonyms gene name
- H2B histone family, member R
- histone 1, H2bj
- histone cluster 1, H2bj
- histone cluster 1 H2B family member j
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-10-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Product files
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