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BIBW2992 Tovok

BIBW2992 Tovok is available 2 times from Biovision labs

1616-5 | BIBW2992 (Tovok) size: 5 mg | 663.35 USD

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1616-1 | BIBW2992 (Tovok) size: 1 mg | 234.19 USD

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Alternative_name Tovok, Afatinib
Description BIBW-2992 is a potent irreversible EGFR/HER2 inhibitor. The potency of BIBW-2992 on the EGFR and HER2 kinases revealed IC₅₀ values of 0.5 nM and 14 nM, respectively. BIBW-2992 is highly selective for these kinases and no additional inhibition of other kinases has been observed.
CAS Number 439081-18-2
Structure Available? Yes
Salt Form No
Molecular Formula C₂₄H₂₅ClFN₅O₃
Molecular Weight 485.94
Cell-Permeable? Yes
Purity ≥99%
Solubilities DMSO
Handling Protect from air and moisture
Tag Line An EGFR/HER2 inhibitor
Storage Condition -20°C
Shipping Condition RT
Shelf Life 24months
MDL Number MFCD12407405
PubChem CID 10184653
SMILES CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
InChi InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34- 16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12, 14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
InChi Key ULXXDDBFHOBEHA-CWDCEQMOSA-N
MSDS Available Yes
Gene targetBIBW2992 Tovok
Short name BIBW2992 (Tovok)
Alternative name BIBW2992 (Tovok)
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BIBW2992 Tovok from Biovision - Gentaur.com
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