BIBW2992 (Tovok)

• Catalog number
  1616-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  Tovok, Afatinib
• Description
  BIBW-2992 is a potent irreversible EGFR/HER2 inhibitor. The potency of BIBW-2992 on the EGFR and HER2 kinases revealed IC₅₀ values of 0.5 nM and 14 nM, respectively. BIBW-2992 is highly selective for these kinases and no additional inhibition of other kinases has been observed.
• CAS Number
  439081-18-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₅ClFN₅O₃
• Molecular Weight
  485.94
• Cell Permeable
  Yes
• Purity
  ≥99%
• Solubilities
  DMSO
• Handling
  Protect from air and moisture
• Tag Line
  An EGFR/HER2 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  RT
• Shelf Life
  24months
• MDL Number
  MFCD12407405
• PubChem CID
  10184653
• PubChem CID Link
• SMILES
  CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
• InChi
  InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34- 16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12, 14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
• InChi Key
  ULXXDDBFHOBEHA-CWDCEQMOSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BIBW2992   Tovok  
• Short name
  BIBW2992 (Tovok)
• Alternative name
  BIBW2992 (Tovok)

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