Recombinant Mouse IL-1 Receptor-Like 1/IL-1RL1/IL-1 R4 Protein(C-6His) 50µg

• Catalog number
  PKSM041050-50µg
• Price
  Please ask
• Size
  50µg

• Activity
  NA
• Synonym
  Interleukin-1 receptor-like 1; Lymphocyte antigen 84; Protein ST2; Protein T1; Il1rl1; DER4; Fit-1; IL-1 R4; IL-1RL1; IL-33R; Ly84; ST2L; ST2V; suppression of tumorigenicity 2
• Sequence
  Ser27-Ala337
• Fusion tag
  C-6His
• Accession
  P14719-2
• Expressed Host
  Human Cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  36.6 kDa
• AP Mol Mass
  55-70 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Background
  ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.
• Technical data
• Gene
  The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  IL-1   Receptor-Like   1/IL-1RL1/IL-1   Protein   C-6His   50µg  
• Gene symbol
  IL1A, IL1B, IL1F10, IL36B, IL19, IL36G, IL25, IL36A, IL17F, IL22
• Short name
  Recombinant Mouse IL-1 Receptor-Like 1/IL-1RL1/IL-1 R4 Protein(C-6His) 50µg
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Interleukin-1 Receptor-Like 1/Interleukin-1RL1/Interleukin-1 R4 Protein(C-6His) 50µg
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:5991
• Gene
  IL1A
• Long gene name
  interleukin 1 alpha
• Synonyms gene
  • IL1
• Synonyms
  • IL1F1
  • IL-1A
  • IL1-ALPHA
• Synonyms name
  • preinterleukin 1 alpha
  • hematopoietin-1
  • pro-interleukin-1-alpha
• GenBank acession
  • M28983
• Locus
  2q14.1
• Discovery year
  2001-06-22
• Entrez gene record
  3552
• Pubmed identfication
  • 8188271
  • 2989698
• RefSeq identity
  • NM_000575
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131315

Gene info

• Identity
  HGNC:5992
• Gene
  IL1B
• Long gene name
  interleukin 1 beta
• Synonyms
  • IL1F2
  • IL-1B
  • IL1-BETA
• GenBank acession
  • M15330
• Locus
  2q14.1
• Discovery year
  1989-03-31
• Entrez gene record
  3553
• Pubmed identfication
  • 2954882
  • 2989698
• RefSeq identity
  • NM_000576
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131344

Gene info

• Identity
  HGNC:15552
• Gene
  IL1F10
• Long gene name
  interleukin 1 family member 10
• Synonyms gene name
  • interleukin 1 family, member 10 (theta)
• Synonyms
  • FKSG75
  • IL-1HY2
  • IL-1F10
  • IL1-theta
  • MGC11983
  • MGC119832
  • MGC119833
• Synonyms name
  • FIL1- theta
  • interleukin-1 receptor antagonist FKSG75
• GenBank acession
  • AY026753
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  84639
• Pubmed identfication
  • 11747621
  • 11991723
  • 11991722
• RefSeq identity
  • NM_173161
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131339

Gene info

• Identity
  HGNC:15564
• Gene
  IL36B
• Long gene name
  interleukin 36 beta
• Synonyms gene
  • IL1F8
• Synonyms gene name
  • interleukin 1 family, member 8 (eta)
• Synonyms
  • FIL1
  • IL-1H2
  • IL-1F8
  • FILI-(ETA)
  • IL1-ETA
  • IL1H2
  • MGC126880
  • MGC126882
• GenBank acession
  • AF201833
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27177
• Pubmed identfication
  • 10625660
  • 10512743
  • 16646978
• RefSeq identity
  • NM_014438
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131338

Gene info

• Identity
  HGNC:5990
• Gene
  IL19
• Long gene name
  interleukin 19
• Synonyms
  • IL-19
  • MDA1
  • ZMDA1
  • IL-10C
  • NG.1
• Synonyms name
  • melanoma differentiation associated protein-like protein
• GenBank acession
  • AF192498
• Locus
  1q32.1
• Discovery year
  2000-03-29
• Entrez gene record
  29949
• Pubmed identfication
  • 11196675
• RefSeq identity
  • NM_153758
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000036387

Gene info

• Identity
  HGNC:15741
• Gene
  IL36G
• Long gene name
  interleukin 36 gamma
• Synonyms gene
  • IL1F9
• Synonyms gene name
  • interleukin 1 family, member 9
• Synonyms
  • IL-1H1
  • IL-1RP2
  • IL-1F9
  • IL1H1
  • IL1E
• Synonyms name
  • interleukin-1 homolog 1
  • interleukin 1-related protein 2
  • interleukin-1 epsilon
• GenBank acession
  • AF200492
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  56300
• Pubmed identfication
  • 10860666
  • 10744718
  • 11991722
  • 11991723
• RefSeq identity
  • NM_019618
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000131336

Gene info

• Identity
  HGNC:13765
• Gene
  IL25
• Long gene name
  interleukin 25
• Synonyms gene
  • IL17E
• Synonyms gene name
  • interleukin 17E
• Synonyms
  • IL-25
  • IL-17E
• GenBank acession
  • AF305200
• Locus
  14q11.2
• Discovery year
  2001-01-26
• Pubmed identfication
  • 11058597
  • 11754819
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000028749

Gene info

• Identity
  HGNC:15562
• Gene
  IL36A
• Long gene name
  interleukin 36 alpha
• Synonyms gene
  • IL1F6
• Synonyms gene name
  • interleukin 1 family, member 6 (epsilon)
• Synonyms
  • FIL1
  • FIL1E
  • IL-1F6
  • IL1(EPSILON)
  • MGC129553
  • MGC129552
• GenBank acession
  • AF201831
• Locus
  2q14.1
• Discovery year
  2002-08-02
• Entrez gene record
  27179
• Pubmed identfication
  • 10625660
• RefSeq identity
  • NM_014440
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000153320

Gene info

• Identity
  HGNC:16404
• Gene
  IL17F
• Long gene name
  interleukin 17F
• Synonyms
  • IL-17F
  • ML-1
  • ML1
• GenBank acession
  • AF384857
• Locus
  6p12.2
• Discovery year
  2002-03-18
• Entrez gene record
  112744
• Pubmed identfication
  • 11591732
  • 11591768
• RefSeq identity
  • NM_052872
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000014845
• Locus Specific Databases
  • LRG_356

Gene info

• Identity
  HGNC:14900
• Gene
  IL22
• Long gene name
  interleukin 22
• Synonyms
  • ILTIF
  • IL-21
  • zcyto18
  • IL-TIF
  • IL-D110
  • TIFa
  • TIFIL-23
  • IL-22
  • MGC79382
  • MGC79384
• Synonyms name
  • IL-10-related T-cell-derived inducible factor
• GenBank acession
  • AF279437
• Locus
  12q15
• Discovery year
  2001-03-12
• Entrez gene record
  50616
• Pubmed identfication
  • 10954742
  • 10875937
• RefSeq identity
  • NM_020525
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000169119
• Locus Specific Databases
  • LRG_1248

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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