Mouse Monoclonal IgG2a Anti-human CD20 [L26]

  • Catalog number
    CD20-1
  • Price
    Please ask
  • Size
    1 ml
  • Availability
    Please contact us to check the availability
  • Immunogen
    B-Cells from human Tonsils
  • Specificity
    Human CD20cy on peripheral and lymphoidal B-cells, germ center of lymph knots.
  • Species reactivity
    Human
  • Product presentation
    Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for at least 100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. Gentaur Art .No. PU002.
  • Product category
    Primary Antibody
  • Antibody s raised in
    Mouse
  • Antibody s isotype
    IgG2a
  • Antibody s clone
    L26
  • Product is supplied as
    liquid concentrate
  • Recommended concentration for use
    1:10 to 1:50
  • Protein concentration
    N/A
  • Positive control
    Lymph nodes, Tonsil
  • Pretreatment
    Improvement of staining with Unmasking Fluid G (Art. No. DE007) or Unmasking Fluid C (Art. No. DE000)
  • Tested applications
    IHC(C, P), FACS
  • Recommended secondary reagent
    We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC (Art. No. PK-6102) or ABC AP (Art. No. AK-5002) systems are applicable.
  • Storage method
    Store at 2-8°C
  • UniProt number
    Go to UniProt/SwissProt
  • Litterature
    1. Zhou l.-Z. and Tedder T. (1993) CD20 Workshop panel report. In Schlossman S.F. et al. Eds. Leucocyte Typing V. White cell differentiation antigens. Oxford University Press, Oxford, N.Y., Tokyo; pp 511-514. 2. Takami T., Qi C., Yamada T., et al. (1989) B20.3. Reactivity and Specificity of L26 (pan-B-cell mAb) on 322 cases of fresh and paraffin-embedded lymphoproliferative diseases. In Kapp W. et al. eds. Leucocyte Typing IV. White Cell Differentiation Antigens. Oxford University Press, Oxford, N.Y., Tokyo; pp 134-136. 3. Mason D.Y., Comans-Bitter WM., Cordell J.L., Verhoeven M.A.J. and van Dongen J.J.M. (1990) Antibody L26 recognizes an intracellular epitope of the B-cell-associated CD20 antigen. Am. J. Pathol. 136; 1215-1222.
  • Tips
    *Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Test
    bio logo supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Latin name
    Mus musculus
  • Gene target
    Monoclonal   IgG2a   CD20   [L26]  
  • Gene symbol
    RPL26, MRPL17, MS4A1
  • Short name
    Bioprime
  • Technique
    Mouse monoclonal, anti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG2a
  • Species
    Human, Humans, Mouses
  • Alternative name
    CD20 (L26), B Cells, human
  • Alternative technique
    murine, antibodies
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    membrane spanning 4-domains A1
  • Synonyms gene
  • Synonyms gene name
    • membrane-spanning 4-domains, subfamily A, member 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1989-05-23
  • Entrez gene record
    931
  • Pubmed identfication
  • Classification
    • Membrane spanning 4-domains
    • CD molecules
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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