CSN2, CT (COP9 Signalosome Complex Subunit 2, ALIEN, COP9, COP9 Constitutive Photomorphogenic Homolog Subunit 2, COPS2, JAB1-containing Signalosome Subunit 2, SGN2, Thyroid Hormone Receptor Interactor 15, Thyroid Receptor-interacting Protein 15, TRIP 15, [CSN2]

• Catalog number
  MBS641501
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  CSN2   COP9   Signalosome   Complex   Subunit   ALIEN   COP9   COP9   Constitutive   Photomorphogenic   Homolog   Subunit   COPS2   JAB1   Signalosome   Subunit   SGN2   Thyroid   Hormone   Receptor   Interactor   Thyroid   Receptor-interacting   Protein   TRIP   [CSN2]  
• Gene symbol
  COPS2, COPS8, CSN2, TRAIP, SERTAD1, PIK3IP1, COPS5, SERTAD2, EIF3I, LRRFIP1
• Short name
  CSN2, CT (COP9 Signalosome Complex Subunit 2, ALIEN, COP9, COP9 Constitutive Photomorphogenic Homolog Subunit 2, COPS2, JAB1- Signalosome Subunit 2, SGN2, Thyroid Hormone Receptor Interactor 15, Thyroid Receptor-interacting Protein 15, TRIP 15, [CSN2]
• Host
  Goat
• Alternative name
  CSN2, CT (COP9 Signalosome aggregate functionnal sequence 2, ALIEN, COP9, COP9 Constitutive Photomorphogenic Homolog functionnal sequence 2, COPS2, JAB1-containing Signalosome functionnal sequence 2, SGN2, Thyroid Hormone Receptor Interactor 15, Thyroid Receptor-interacting Protein 15, TRIP 15, [CSN2]
• Tissue
  thyroid

Gene info

• Identity
  HGNC:30747
• Gene
  COPS2
• Long gene name
  COP9 signalosome subunit 2
• Synonyms gene name
  • COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
• Synonyms
  • TRIP15
  • ALIEN
  • CSN2
• GenBank acession
  • AF212227
• Locus
  15q21.1
• Discovery year
  2004-11-03
• Entrez gene record
  9318
• Pubmed identfication
  • 7776974
  • 9535219
• RefSeq identity
  • NM_004236
• Classification
  • COP9 signalosome
• VEGA ID
  OTTHUMG00000172324

Gene info

• Identity
  HGNC:24335
• Gene
  COPS8
• Long gene name
  COP9 signalosome subunit 8
• Synonyms gene name
  • COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
• Synonyms
  • COP9
  • CSN8
  • MGC1297
  • SGN8
• Locus
  2q37.3
• Discovery year
  2004-01-05
• Entrez gene record
  10920
• Pubmed identfication
  • 7634324
  • 12732143
• RefSeq identity
  • NM_006710
• Classification
  • COP9 signalosome
• VEGA ID
  OTTHUMG00000133297

Gene info

• Identity
  HGNC:2447
• Gene
  CSN2
• Long gene name
  casein beta
• Synonyms gene
  • CASB
• GenBank acession
  • X17070
• Locus
  4q13.3
• Discovery year
  1987-09-11
• Entrez gene record
  1447
• Pubmed identfication
  • 1577486
• VEGA ID
  OTTHUMG00000129409

Gene info

• Identity
  HGNC:30764
• Gene
  TRAIP
• Long gene name
  TRAF interacting protein
• Synonyms
  • TRIP
  • RNF206
• Synonyms name
  • ring finger protein 206
• GenBank acession
  • BC019283
• Locus
  3p21.31
• Discovery year
  2006-01-09
• Entrez gene record
  10293
• Pubmed identfication
  • 9104814
• RefSeq identity
  • NM_005879
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000158269

Gene info

• Identity
  HGNC:17932
• Gene
  SERTAD1
• Long gene name
  SERTA domain containing 1
• Synonyms
  • SEI1
  • TRIP-Br1
• Synonyms name
  • CDK4-binding protein p34SEI
  • transcriptional regulator interacting with the PHD-bromodomain 1
• GenBank acession
  • AF117959
• Locus
  19q13.2
• Discovery year
  2004-02-16
• Entrez gene record
  29950
• Pubmed identfication
  • 6434876
  • 10580009
• RefSeq identity
  • NM_013376
• VEGA ID
  OTTHUMG00000182594

Gene info

• Identity
  HGNC:24942
• Gene
  PIK3IP1
• Long gene name
  phosphoinositide-3-kinase interacting protein 1
• Synonyms
  • HGFL
  • MGC17330
  • TrIP
• Synonyms name
  • transmembrane inhibitor of PI3K
• GenBank acession
  • BC011049
• Locus
  22q12.2
• Discovery year
  2007-04-13
• Entrez gene record
  113791
• Pubmed identfication
  • 17475214
• RefSeq identity
  • NM_052880
• VEGA ID
  OTTHUMG00000151256

Gene info

• Identity
  HGNC:2240
• Gene
  COPS5
• Long gene name
  COP9 signalosome subunit 5
• Synonyms gene name
  • COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5
  • COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
• Synonyms
  • JAB1
  • SGN5
  • MOV-34
  • CSN5
• GenBank acession
  • U65928
• Locus
  8q13.1
• Discovery year
  2000-06-08
• Entrez gene record
  10987
• Pubmed identfication
  • 8837781
  • 9341143
• Classification
  • COP9 signalosome
  • JAMM/MPN+ metallopeptidase family
• VEGA ID
  OTTHUMG00000164563

Gene info

• Identity
  HGNC:30784
• Gene
  SERTAD2
• Long gene name
  SERTA domain containing 2
• Synonyms
  • TRIP-Br2
  • KIAA0127
  • Sei-2
• Synonyms name
  • transcriptional regulator interacting with the PHS-bromodomain 2
• GenBank acession
  • D50917
• Locus
  2p14
• Discovery year
  2004-02-16
• Entrez gene record
  9792
• Pubmed identfication
  • 8590280
  • 11331592
• RefSeq identity
  • NM_014755
• VEGA ID
  OTTHUMG00000152678

Gene info

• Identity
  HGNC:3272
• Gene
  EIF3I
• Long gene name
  eukaryotic translation initiation factor 3 subunit I
• Synonyms gene
  • EIF3S2
• Synonyms gene name
  • eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa
  • eukaryotic translation initiation factor 3, subunit I
• Synonyms
  • TRIP-1
  • eIF3-beta
  • eIF3-p36
• GenBank acession
  • U39067
• Locus
  1p35.2
• Discovery year
  1998-11-26
• Entrez gene record
  8668
• Pubmed identfication
  • 7566156
  • 8995409
• RefSeq identity
  • NM_003757
• Classification
  • Eukaryotic translation initiation factor 3
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000007364

Gene info

• Identity
  HGNC:6702
• Gene
  LRRFIP1
• Long gene name
  LRR binding FLII interacting protein 1
• Synonyms gene name
  • leucine rich repeat (in FLII) interacting protein 1
• Synonyms
  • FLAP-1
  • FLIIAP1
  • TRIP
  • GCF-2
  • HUFI-1
  • GCF2
• Synonyms name
  • GC-binding factor 2
• GenBank acession
  • AJ223075
• Locus
  2q37.3
• Discovery year
  1999-02-15
• Entrez gene record
  9208
• Pubmed identfication
  • 9705290
  • 9525888
  • 16199883
• RefSeq identity
  • NM_004735
• VEGA ID
  OTTHUMG00000133339

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