Carfilzomib,20S Proteasome inhibitor

Research Area s

Cancer , Cancer Growth Inhibitors , Proteasome Inhibitors
Category

Small Molecules
Product Type

Inhibitor
CAS No

868540-17-4
MolecularFormula

C40H57N5O7
Molecular Weight

719.9
Purity

>98% (TLC); NMR (Conforms)
Solubility

Soluble in DMSO (80 mg/ml), or ethanol (25 mg/ml)
Appearance

White powder
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.