N-Oxalylglycine

  • Catalog number
    B1084-50
  • Price
    Please ask
  • Size
    50 mg
  • Alternative_name
    2-(Carboxymethylamino)-2-oxoacetic acid
  • Description
    N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell-permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC₅₀s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC₅₀ values of 2.1 and 5.6 μM, respectively.
  • CAS Number
    5262-39-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₄H₅NO₅
  • Molecular Weight
    147.1
  • Cell Permeable
    Yes
  • Purity
    ≥95% by HPLC
  • Solubilities
    DMSO (~10 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A cell-permeable inhibitor of α-ketoglutarate-dependent enzymes
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00913253
  • PubChem CID
    3080614
  • SMILES
    C(C(=O)O)NC(=O)C(=O)O
  • InChi
    InChI=1S/C4H5NO5/c6-2(7)1-5-3(8)4(9)10/h1H2,(H,5,8)(H,6,7)(H,9,10)
  • InChi Key
    BIMZLRFONYSTPT-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    N-Oxalylglycine
  • Alternative name
    N-Oxalylglycine
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