N-Oxalylglycine
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Catalog numberB1084-50
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PricePlease ask
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Size50 mg
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Alternative_name2-(Carboxymethylamino)-2-oxoacetic acid
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DescriptionN-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell-permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC₅₀s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC₅₀ values of 2.1 and 5.6 μM, respectively.
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CAS Number5262-39-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₄H₅NO₅
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Molecular Weight147.1
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Cell PermeableYes
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Purity≥95% by HPLC
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SolubilitiesDMSO (~10 mg/ml)
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HandlingProtect from air and moisture
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Tag LineA cell-permeable inhibitor of α-ketoglutarate-dependent enzymes
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD00913253
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PubChem CID3080614
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SMILESC(C(=O)O)NC(=O)C(=O)O
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InChiInChI=1S/C4H5NO5/c6-2(7)1-5-3(8)4(9)10/h1H2,(H,5,8)(H,6,7)(H,9,10)
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InChi KeyBIMZLRFONYSTPT-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameN-Oxalylglycine
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Alternative nameN-Oxalylglycine
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