Suz12 polyclonal antibody
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Catalog number
6832-25
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Price
Please ask
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Size
25 μg
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Antibody Target
Suz12
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Target Alternative Name
CHET9, JJAZ1
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Antibody Type
Polyclonal
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Species Reactivities
Human, mouse.
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Immunogen Sequence
Polyclonal antibody raised in rabbit against the N-terminus of recombinant human Suz12 protein (Suppressor of Zeste 12 protein homolog).
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Accession
Q15022
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Gene Id
23512
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In PBS with 0.05% sodium azide and 0.05% ProClin 300.
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Purification
Protein G purified
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Application
Western blot, ChIP.
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Positive Control
Western blot: HeLa cells, ChIP: Mouse ES cells.
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Application And Usages
ChIP: 10 µg/ChIP, Western Blot: 1:1000
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Description
Suz12 is a Polycomb group (PcG) protein. These proteins form multiprotein complexes, which keep homeotic genes in a transcriptionally repressive state throughout development. PcG proteins are not required to initiate repression, but maintain it during later stages of development. They probably act via the methylation of histones. Suz12 is a component of the PRC2 complex, which is composed of EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7, and methylates ‘Lys-9’ and ‘Lys-27’ of histone H3.
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Storage Condition
-20 °C
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Shipping Condition
gel pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
Verified
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Immunocytochemistry Verified
Not Verified
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Immunofluorescence Verified
Not Verified
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Immunoprecipitation Verified
Not Verified
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ELISA Verified
Verified
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ChIP Verified
Not Verified
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Dot Blot Verified
Not Verified
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Flow Cytometry Verified
Not Verified
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translation
anticorps
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Gene target
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Gene symbol
SUZ12, SUZ12P2, SUZ12P1
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Short name
Suz12 polyclonal antibody
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Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Isotype
Rabbit IgG
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Alternative name
Suz12 polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies
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Gene info
Gene info
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Identity
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Gene
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Long gene name
SUZ12 pseudogene 2
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Synonyms gene name
- suppressor of zeste 12 homolog pseudogene 2
- SUZ12 polycomb repressive complex 2 subunit pseudogene 2
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Locus
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Discovery year
2012-04-04
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Entrez gene record
Gene info
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Identity
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Gene
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Long gene name
SUZ12 pseudogene 1
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Synonyms gene
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Synonyms gene name
- suppressor of zeste 12 homolog pseudogene
- suppressor of zeste 12 homolog pseudogene 1
- SUZ12 polycomb repressive complex 2 subunit pseudogene 1
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GenBank acession
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Locus
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Discovery year
2005-12-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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