FRS2 alpha, phosphorylated (Tyr196) (Fibroblast Growth Factor Receptor Substrate 2, RS2, Suc-associated Neurotrophic Factor-induced Tyrosine-phosphorylated Target, SNT)
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Catalog numberMBS610569
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PricePlease ask
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Size0.1 mL
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Products_typeAntibody
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Products_short_name[FRS2 alpha]
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Products_name_syn[Anti -FRS2 alpha, phosphorylated (Tyr196) (Fibroblast Growth Factor Receptor Substrate 2, RS2, Suc-associated Neurotrophic_x000B_Factor-induced Tyrosine-phosphorylated Target, SNT)]
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Other_names[fibroblast growth factor receptor substrate 2; Fibroblast growth factor receptor substrate 2; fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1; fibroblast growth factor receptor substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1]
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Other_gene_names[FRS2; FRS2; SNT; SNT1; FRS2A; SNT-1; FRS2alpha; FGFR substrate 2; SNT-1]
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ClonalityPolyclonal
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ReactivityHuman, Mouse
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SpecificityRecognizes endogenous levels of human FRS2-alpha only when phosphorylated at tyrosine 196 at 85kD. Does not crossreact with unrelated tyrosine phosphorylated proteins. Species Crossreactivity
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PurityAffinity Purified Purified by Protein A and peptide affinity chromatography.
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FormSupplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationWestern Blot (WB)
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DescriptionThe FRS2 alpha, phosphorylated (Tyr196) (Fibroblast Growth Factor Receptor Substrate 2, RS2, Suc-associated Neurotrophic Factor- Tyrosine-phosphorylated , SNT) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolFRS2, FRS3, ZRSR2
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Short nameFRS2 alpha, phosphorylated (Tyr196) (Fibroblast Growth Factor Receptor Substrate 2, RS2, Suc-associated Neurotrophic Factor- Tyrosine-phosphorylated , SNT)
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HostRabbit
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IsotypeIgG
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Alternative nameFRS2 a, phosphorylated (Tyr196) (Fibroblast Growth Factor Receptor Substrate 2, RS2, Suc-associated Neurotrophic Factor-induced Tyrosine-phosphorylated Target, SNT)
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Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor receptor substrate 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-05-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor receptor substrate 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-05-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
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Synonyms gene
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Synonyms gene name
- U2(RNU2) small nuclear RNA auxiliary factor 1-like 2
- U2 small nuclear RNA auxiliary factor 1-like 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-09-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- U11/U12 di-snRNP
- Zinc fingers CCCH-type
- RNA binding motif containing
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VEGA ID
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Locus Specific Databases