Gremlin-2, Cysteine knot superfamily 1, BMP antagonist 2, Protein related to DAN and cerberus, DAN domain family member 3
Inhibitor of BMP-2, -4, and -7
Purity by SDS-PAGE
Test in process
Physical form description
Sterile filtered and lyophilized with no additives
Reconstitute to 1 mg/ml with sterilized dH₂O. Pipette to dissolve the protein pellet completely
Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors. Recombinant human Gremlin-2 is a N-terminus His-tagged protein that was expressed from E. coli.
Centrifuge the vial prior to opening.
For Research Use Only! Not to be used in humans
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
Gremlin 2, recombinant
Gremlin 2, H. sapiens recombinant