anti-NOX3 Antibody

  • Catalog number
    7925
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4).
  • Gene names
    NAPDH oxidase 3, NOX-3, GP91-3, MOX2, MOX-2
  • Antibodie s label
    unlabelled serum
  • Purity
    NOX3 antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins.
  • Antigen
    NOX3 antibody was made against a 15 amino acid peptide near the amino terminus of human NOX3.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
  • Antibody advice
    NOX3 antibody can be used for detection of NOX3 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    NOX3 antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    NOX3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
  • Works with
    Human, Mouse
  • Omim nr
    11136626
  • Ncbi nr
    NP_056533
  • KDa
    Predicted: 62 kDa Observed: 72 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    50508
  • GENE symbol
    NOX3
  • Antigene name
    NADPH oxidase 3
  • Source
    homo sapiens
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    NOX3  
  • Gene symbol
    NOX3
  • Short name
    anti-NOX3 Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toNOX3 (antibody to-)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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