anti-NOX3 Antibody
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Catalog number7925
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoThe NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4).
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Gene namesNAPDH oxidase 3, NOX-3, GP91-3, MOX2, MOX-2
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Antibodie s labelunlabelled serum
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PurityNOX3 antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toNOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins.
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AntigenNOX3 antibody was made against a 15 amino acid peptide near the amino terminus of human NOX3.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceNOX3 antibody can be used for detection of NOX3 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azideNOX3 antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atNOX3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works withHuman, Mouse
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Omim nr11136626
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Ncbi nrNP_056533
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KDaPredicted: 62 kDa Observed: 72 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr50508
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GENE symbolNOX3
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Antigene nameNADPH oxidase 3
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Sourcehomo sapiens
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNOX3
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Short nameanti-NOX3 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toNOX3 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameNADPH oxidase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-05-30
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data