TNF-RI, Mouse, mAb 55R-170[TNF-RI]

Products_type

Antibody
Products_gene_name

[TNF-RI]
Reactivity

Mouse
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus
Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.

Gene target

TNF-RI mAb 55R-170[TNF-RI]
Gene symbol

TNF, TNFRSF1A, LNCRI, TNFRSF1B, LTBR, CLIP1, BTAF1, ABCB1
Short name

TNF-RI, Mouse, mAb 55R-170[TNF-RI]
Technique

Mouse, mouses
Host

Armenian hamster
Species

Mouse, Mouses
Alternative name

tumor necrosis factor-RI, Mouse, monoclonal 55R-170[tumor necrosis factor-RI]
Alternative technique

murine
Alternative to gene target

tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943

Identity

HGNC:11916
Gene

TNFRSF1A
Long gene name

TNF receptor superfamily member 1A
Synonyms gene
- TNFR1
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
Synonyms
- TNF-R
- TNFAR
- TNFR60
- TNF-R-I
- CD120a
- TNF-R55
GenBank acession
- M75866
Locus

12p13.31
Discovery year

1991-01-15
Entrez gene record

7132
Pubmed identfication
- 1655358
- 2158863
RefSeq identity
- NM_001065
Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
VEGA ID

OTTHUMG00000168267
Locus Specific Databases
- INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
- LRG_193

Identity

HGNC:11917
Gene

TNFRSF1B
Long gene name

TNF receptor superfamily member 1B
Synonyms gene
- TNFR2
Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
Synonyms
- TNFBR
- TNFR80
- TNF-R75
- TNF-R-II
- p75
- CD120b
GenBank acession
- M32315
Locus

1p36.22
Discovery year

1991-01-15
Entrez gene record

7133
Pubmed identfication
- 2158863
- 8702885
RefSeq identity
- NM_001066
Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
VEGA ID

OTTHUMG00000001829

Identity

HGNC:10461
Gene

CLIP1
Long gene name

CAP-Gly domain containing linker protein 1
Synonyms gene
- RSN
Synonyms gene name
- restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
- CAP-GLY domain containing linker protein 1
Synonyms
- CYLN1
- CLIP170
- CLIP
- CLIP-170
Synonyms name
- restin
Locus

12q24.31
Discovery year

1993-06-10
Entrez gene record

6249
Pubmed identfication
- 8222754
RefSeq identity
- NM_002956
VEGA ID

OTTHUMG00000168922

Identity

HGNC:17307
Gene

BTAF1
Long gene name

B-TFIID TATA-box binding protein associated factor 1
Synonyms gene name
- BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170 kD (Mot1 homolog, S. cerevisiae)
- BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
Synonyms
- TAFII170
- TAF172
- MOT1
- TAF-172
- TAF(II)170
Synonyms name
- Mot1 homolog (S. cerevisiae)
GenBank acession
- AJ001017
Locus

10q23.32
Discovery year

2001-12-03
Entrez gene record

9044
Pubmed identfication
- 9342322
- 9488487
RefSeq identity
- NM_003972
Classification
- Armadillo like helical domain containing
VEGA ID

OTTHUMG00000018752

Identity

HGNC:40
Gene

ABCB1
Long gene name

ATP binding cassette subfamily B member 1
Synonyms gene
- PGY1
- MDR1
- CLCS
Synonyms gene name
- colchicin sensitivity
- ATP-binding cassette, sub-family B (MDR/TAP), member 1
Synonyms
- P-gp
- CD243
- GP170
- ABC20
- p-170
Synonyms name
- multidrug resistance protein 1
GenBank acession
- M14758
Locus

7q21.12
Discovery year

1986-01-01
Entrez gene record

5243
Pubmed identfication
- 3027054
RefSeq identity
- NM_000927
Classification
- ATP binding cassette subfamily B
- CD molecules
VEGA ID

OTTHUMG00000023393