CD43 Antibody
-
Catalog numberGEN438321
-
PricePlease ask
-
Size100ug
-
-
Also known asCD43
-
Other namesleukosialin; Leukosialin; leukosialin; galactoglycoprotein; leukocyte sialoglycoprotein; sialophorin (gpL115, leukosialin, CD43); sialophorin; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD_antigen: CD43
-
CategoryAntibodies
-
SubcategoryMnoclonal antibodies
-
Gene nameSPN
-
Gene name synonimsN/A
-
Other gene namesSPN; SPN; LSN; CD43; GALGP; GPL115; CD43; GALGP
-
ClonalityMonoclonal
-
Immunoglobulin isotypeIgG1, kappa
-
CloneDF-T1
-
Host organismMouse (Mus musculus)
-
Species reactivityHuman (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivityIt recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification methodN/A
-
Form AppearanceN/A
-
ConcentrationN/A
-
Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
-
Tested applicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
-
PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolSPN
-
Short nameCD43 Antibody
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
Alternative nameAnti-CD43
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namesialophorin
-
Synonyms gene name
- sialophorin (gpL115, leukosialin, CD43)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1988-08-31
-
Pubmed identfication
-
Classification
- CD molecules
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data