1400W dihydrochloride
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Catalog number2055-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
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DescriptionCell-permeable. A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd ≤ 7 nM). In contrast, inhibition of nNOS and eNOS is weaker and rapidly reversible with Kᵢ values of 2 and 50 µM respectively. Inhibits tumor growth in vivo. Prevents circulatory failure but not organ injury induced by endotoxin. Displays protective effects in oxygen-deprived brain slices.
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CAS Number214358-33-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₀H₁₅N₃ . 2HCl
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Molecular Weight250.17
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Cell PermeableYes
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Purity≥98% by NMR
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SolubilitiesWater (100 mM)
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HandlingProtect from air and moisture
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Tag LineA highly selective iNOS inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD03428622
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PubChem CID2733515
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SMILESCC(=NCC1=CC(=CC=C1)CN)N.Cl.Cl
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InChiInChI=1S/C10H15N3.2ClH/c1-8(12)13-7-10-4-2-3-9(5-10)6-11;;/h2-5H,6-7,11H2,1H3,(H2,12,13);2*1H
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InChi KeyWDJHSQZCZGPGAA-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short name1400W dihydrochloride
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Alternative name1400W dihydrochloride
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