(1E,3R,4S)-1-[(3'aS,4'R,5'R,6'aR)-5'-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalen]-4'-yl]-4-methyl-1-octen-6-yn-3-ol
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Catalog numberD473515
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PricePlease ask
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Size0,25 mg
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Chemical available in other sizesPlease inquire size and price
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Stock availabilityPending QC
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Cas number910916-95-9
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Chemical s molecular weight476.76
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Chemical s main applications(1E,3R,4S)-1-[(3'aS,4'R,5'R,6'aR)-5'-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalen]-4'-yl]-4-methyl-1-octen-6-yn-3-ol is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud's phenomenon and ischemia.
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Chemical s categoryChiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
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Chemical s formulaC28H48O4Si
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Physical propertiesClear Oil
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Melting temperatureNo Data Available
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Boiling temperatureNo Data Available
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Chemical s soluble inDCM, Ethyl Acetate, Methanol
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Stability conditionsNo Data Available
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StorageNo Data Available
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DescriptionA methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
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Gene target
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Gene symbolYWHAZ, TRR-ACG1-3, TRF-GAA1-3, TRR-CCG1-3, MIR3130-1, TRW-CCA3-3, TRE-CTC1-3, TRP-CGG1-3, TRH-GTG1-3, TRI-GAT1-3
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Short name(1E 3R 4S)-1-[(3'aS 4'R 5'R 6'aR)-5'-[[(1 1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5 5-dimethylspiro[1 3-dioxane-2 2'(1'H)-pentalen]-4'-yl]-4-methyl-1-octen-6-yn-3-ol
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Alternative name(1E,3R,4S)-1-[(3'aS,4'R,5'R,6'aR)-5'-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-5,5-dimethylspiro[1,3-dioxane-2,2'(1'H)-pentalen]-4'-yl]-4-methyl-1-octen-6-yn-3-ol
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Gene info
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Identity
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Gene
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Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
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Synonyms gene
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Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-09-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametRNA-Arg (anticodon ACG) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA arginine 21 (anticodon ACG)
- transfer RNA-Arg (ACG) 1-1
- transfer RNA-Arg (ACG) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Phe (anticodon GAA) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA phenylalanine 11 (anticodon GAA)
- transfer RNA-Phe (GAA) 1-1
- transfer RNA-Phe (GAA) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Arg (anticodon CCG) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA arginine 19 (anticodon CCG)
- transfer RNA-Arg (CCG) 1-1
- transfer RNA-Arg (CCG) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene namemicroRNA 3130-1
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Synonyms gene
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Synonyms gene name
- microRNA 3130-3
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Synonyms
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Locus
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Discovery year2010-04-30
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Trp (anticodon CCA) 3-3
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Synonyms gene
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Synonyms gene name
- transfer RNA tryptophan 3 (anticodon CCA)
- transfer RNA-Trp (CCA) 3-1
- transfer RNA-Trp (CCA) 3-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Glu (anticodon CTC) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA glutamic acid 22 (anticodon CUC)
- transfer RNA-Glu (CTC) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Pro (anticodon CGG) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA proline 8 (anticodon CGG)
- transfer RNA-Pro (CGG) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-His (anticodon GTG) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA histidine 9 (anticodon GUG)
- transfer RNA-His (GTG) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon GAT) 1-3
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 26 (anticodon GAU)
- transfer RNA-Ile (GAT) 1-3
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
