MK-8931

  • Catalog number
    B1315-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide; MK-8931
  • Description
    MK-8931 is a potent BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
  • CAS Number
    1286770-55-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₇H₁₇F₂N₅O₃S
  • Molecular Weight
    409.41
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>30 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent BACE1 inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    51352361
  • SMILES
    CC1(CS(=O)(=O)N(C(=N1)N)C)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)F)F
  • InChi
    InChI=1S/C17H17F2N5O3S/c1-17(9-28(26,27)24(2)16(20)23-17)12-7-11(4-5-13(12)19)22-15(25)14-6-3-10(18)8-21-14/h3-8H,9H2,1-2H3,(H2,20,23)(H,22,25)/t17-/m0/s1
  • InChi Key
    YHYKUSGACIYRML-KRWDZBQOSA-N
  • MSDS Available
    Yes
  • Gene target
    MK-8931  
  • Gene symbol
    MVK, STYXL1, MDK, MAPKAPK3, EPCAM
  • Short name
    MK-8931
  • Alternative name
    MK-8931
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