MK-8931
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Catalog numberB1315-5
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PricePlease ask
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Size5 mg
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Alternative_name(R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide; MK-8931
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DescriptionMK-8931 is a potent BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
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CAS Number1286770-55-5
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₁₇F₂N₅O₃S
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Molecular Weight409.41
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>30 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent BACE1 inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID51352361
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SMILESCC1(CS(=O)(=O)N(C(=N1)N)C)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)F)F
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InChiInChI=1S/C17H17F2N5O3S/c1-17(9-28(26,27)24(2)16(20)23-17)12-7-11(4-5-13(12)19)22-15(25)14-6-3-10(18)8-21-14/h3-8H,9H2,1-2H3,(H2,20,23)(H,22,25)/t17-/m0/s1
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InChi KeyYHYKUSGACIYRML-KRWDZBQOSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolMVK, STYXL1, MDK, MAPKAPK3, EPCAM
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Short nameMK-8931
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Alternative nameMK-8931
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Gene info
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Identity
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Gene
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Long gene namemevalonate kinase
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Synonyms gene name
- mevalonate kinase (mevalonic aciduria)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-10-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameserine/threonine/tyrosine interacting like 1
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Synonyms gene
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Synonyms gene name
- dual specificity phosphatase 24 (putative)
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-01-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAP kinase phosphatases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemidkine
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Synonyms gene
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Synonyms gene name
- neurite growth-promoting factor 2
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Synonyms
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Locus
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Discovery year1991-07-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMAPK activated protein kinase 3
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Synonyms gene name
- mitogen-activated protein kinase-activated protein kinase 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-03-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MAPK activated protein kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameepithelial cell adhesion molecule
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Synonyms gene
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Synonyms gene name
- antigen identified by monoclonal antibody AUA1
- tumor-associated calcium signal transducer 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-10-02
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Entrez gene record
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Pubmed identfication
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Classification
- MicroRNA protein coding host genes
- CD molecules
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VEGA ID
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Locus Specific Databases