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Target antigen
Syndecan1
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
rat Theoretical reactivity:human
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Analyses
WB
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Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan-1 (218-251aa ENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKE), different from the related mouse sequence by six amino acids, and from the related rat sequence by four amino acids.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the Syndecan1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The Syndecan1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Syndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
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Related articles
1. Ala-Kapee M, Nevanlinna H, Mali M, Jalkanen M, Schröder J (September 1990). "Localization of gene for human syndecan, an integral membrane proteoglycan and a matrix receptor, to chromosome 2". Somat. Cell Mol. Genet.16 (5): 501–5. 2. Mali M, Jaakkola P, Arvilommi AM, Jalkanen M (April 1990). "Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans". J. Biol. Chem. 265 (12): 6884–9.
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Gene Name
SDC1
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Protein Name
Syndecan-1
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Gene Full Name
syndecan 1
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Synonyms
CD_antigen antibody|CD138 antibody|CD138 antigen antibody|heparan sulfate proteoglycan fibroblast growth factor receptor antibody|SDC antibody|Sdc1 antibody|SDC1_HUMAN antibody|SYND1 antibody|Syndecan 1 antibody|syndecan proteoglycan 1 antibody|Syndecan-1 antibody
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Uniprot ID
P18827
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Entrez GeneID
6382
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
