HLA-DRB1 polyclonal antibody

Alternative Name

DRB1;HLA-DR1B;HLA-DRB;SS1
Immunogen

Recombinant protein of human HLA-DRB1
Swiss Prot

P01911/P01912/Q29974
Reactivity

Human,Mouse
Applications

WB IF
Application_all

WB1:500 - 1:2000 IF1:50 - 1:100
Product

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage Stability

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity

HLA-DRB1 polyclonal antibody detects endogenous levels of HLA-DRB1 protein.
Usage

Western blot analysis of extracts of various cell lines, using HLA-DRB1 antibody.
BiowMW

~ 30 kDa
Note

For research use only, not for use in diagnostic procedure.
Properties

If you buy Antibodies supplied by Bioworld they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation

anticorps

Gene target

HLA-DRB1
Gene symbol

HLA-DRB1, HLA-DPA2, HLA-DOA, HLA-DQA1, HLA-N, HLA-DPB1, HLA-DQA2, HLA-DQB2, HLA-W, HLA-DRA
Short name

HLA-DRB1 polyclonal antibody
Technique

Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Rabbit
Alternative name

major histocompatibility aggregate, class II, DR b 1 polyclonal (antibody to-)
Alternative technique

polyclonals, antibodies
Alternative to gene target

major histocompatibility complex, class II, DR beta 1, DRB1 and DRw10 and HLA-DR1B and HLA-DRB and SS1, HLA-DRB1 and IDBG-80863 and ENSG00000196126 and 100996809,3123, peptide antigen binding, Cell surfaces

Identity

HGNC:4939
Gene

HLA-DPA2
Long gene name

major histocompatibility complex, class II, DP alpha 2 (pseudogene)
Synonyms gene
- HLA-DP2A
GenBank acession
- X01634
Locus

6p21.32
Discovery year

1986-01-01
Entrez gene record

646702
Pubmed identfication
- 6597088
Classification
- Histocompatibility complex
VEGA ID

OTTHUMG00000031061
Locus Specific Databases
- IMGT/HLA Database

Name

Blood Grouping and Crossmatching
Concept

Scope note: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.
Tree numbers
- E01.370.225.625.120
- E01.370.225.812.385.120
- E05.200.625.120
- E05.200.812.385.120
- E05.478.594.385.120
Qualifiers

ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data