iPSC differentiation

Service category

S400 iPSC Services
Shipping recommendations

dry ice
Synthesis time

vary
Description

Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells. The iPSC technology was pioneered by Shinya Yamanaka’s lab in Kyoto, Japan, who showed in 2006 that the introduction of four specific genes encoding transcription factors could convert adult cells into pluripotent stem cells.[1] He was awarded the 2012 Nobel Prize along with Sir John Gurdon "for the discovery that mature cells can be reprogrammed to become pluripotent

Gene target

differentiation
Gene symbol

NEUROD2, MYADML, NEUROD4
Short name

iPSC differentiation
Technique

ipsc, ipscs are induced pluripotent stem cells by yamanaka or thomson factors. They can be direived from fibroblasts, adipocytes but all other cell types too.
Alternative name

iPSC differentiation
Alternative technique

stemcells

Name

Cellular Reprogramming Techniques
Concept

Scope note: Procedures used for the induction of CELLULAR REPROGRAMMING to change the terminal phenotype of a cell, such as the generation of INDUCED PLURIPOTENT STEM CELLS from differentiated adult cells by the forced expression of specific genes.
Tree numbers
- E05.200.500.380
- E05.242.378
- E05.393.085
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data