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MIR339 Adenovirus (Human)

MIR339 Adenovirus (Human) is available 1 time from Abm adinovirus labs

108246A | MIR339 Adenovirus (Human) size: 250ul | Place ask USD

Catalog number 108246A
PricePlace ask USD
Size 250ul
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1. Gene info
Identity31776
GeneMIR339
Long gene name microRNA 339
Synonyms gene
Synonyms
Locus7p22.3
Discovery year 2004-07-22
Entrez gene record442907
RefSeq identity
Classification
  • MicroRNAs
Additional information
PubMedmiR-339-5p regulates BACE1 expression in human brain cells.
miR-339-5p expression is downregulated in tumors harboring wild-type TP53, suggesting that reduction of miR-339-5p level helps to suppress the p53 response in p53-competent tumor cells.
Results show that Dicer is responsible for the generation of the mature miR-222 and -339, which suppress ICAM-1 expression on tumor cells.
Observational study of gene-disease association. (HuGE Navigator)
miR-339-5p inhibits migration and invasion in ovarian cancer by targeting NACC1 and BCL6. miR-339-5p may be a biomarker of metastasis in ovarian cancer; NACC1 had a predictive value for ovarian cancer progression
Data indicate RNA binding protein NOVA1 as a target of microRNA miR-339.
MiR-339-5p inhibits breast cancer cell migration and invasion
The results highlighted an important role of microRNA-339-5p in suppression of colorectal tumorigenesis, and also revealed that regulating the p53 function is an important mechanism for microRNA-339-5p in tumor suppression.
Our results indicated that miR-339-5p may serve as a tumor suppressor and play important role in inhibiting tumor invasion. Our work implicates that miR-339-5p may serve as a prognostic marker and molecular therapeutic target in hepatocellular carcinoma
Transduction of miR-339 and miR-766 expressing viruses into colon cancer cell lines (SW480 and HCT116) decreased DNMT3B expression (1.5, 3-fold) and (3, 4-fold), respectively. In addition, DNA methylation of some tumor suppressor genes decreased.
Gene ontology - Cellular componentextracellular space
Entrez GenemicroRNA 339  (MIR339)
Shipping handling and storage MIR339 Adenovirus (Human) should be stored according to label on the vial.
Additional information The MIR339 Adenovirus (Human) could be additionally purified if wanted from the customer. Please contact our sales representative to obtain more information.
Detection and sensitivity Before using MIR339 Adenovirus (Human) please read the package insert. It is intended for Human reactivity. Accession Number: NR_029898
Product type Adenovirus
Performance and applications Please contact Gentaur's support by livechat, email or phone in order to receive the requested information. The product is for research use only.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene targetMIR339 Adenovirus
Short name MIR339 Adenovirus ( )
Species Human
Alternative name MIR339 Adenovirus (H. sapiens)
Virus adenovirus
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