Antithrombin III Antibody

• Catalog number
  PA2218
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Antithrombin III
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat Predicted to work with: mouse
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III(93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Antithrombin III Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Antithrombin III Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Serpin peptidase inhibitor, clade C(antithrombin), member 1, also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
• Related articles
  1. Baud, O., Picard, V., Durand, P., Duchemin, J., Proulle, V., Albenc-Gelas, M., Devictor, D., Dreyfus, M. Intracerebral hemorrhage associated with a novel antithrombin gene mutation in a neonate. J. Pediat. 139: 741-743, 2001. 2. Fischer, A. M., Cornu, P., Sternberg, C., Meriane, F., Dautzenberg, M. D., Chafa, O., Beguin, S., Desnos, M. Antithrombin III Alger: a new homozygous AT III variant. Thromb. Haemost. 55: 218-221, 1986.
• Gene Name
  SERPINC1
• Protein Name
  Antithrombin-III
• Gene Full Name
  serpin peptidase inhibitor, clade C(antithrombin), member 1
• Synonyms
  ANT3_HUMAN antibody|Antithrombin antibody|Antithrombin III antibody|Antithrombin-III antibody|AntithrombinIII antibody|AT 3 antibody|AT III antibody|AT3 antibody|AT3D antibody|ATIII antibody|MGC22579 antibody|Serine(or cysteine) proteinase inhibitor clade C(antithrombin) member 1 antibody|Serine cysteine proteinase inhibitor clade C member 1 antibody|Serine proteinase inhibitor clade C member 1 antibody|SERPIN C1 antibody|Serpin peptidase inhibitor clade C(antithrombin) member 1 antibody|SERPINC1 antibody|THPH7 antibody
• Uniprot ID
  P01008
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Antithrombin   III  
• Gene symbol
  CPLX3, MGAT3, MGST3, P4HA3, CASP5, IGHVIII-82, THAP4, MT-CSB3, IGHVIII-44, IGHVIII-67-4
• Short name
  Antithrombin III Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Antithrombin III (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:27652
• Gene
  CPLX3
• Long gene name
  complexin 3
• Synonyms
  • CPX-III
• GenBank acession
  • BC018026
• Locus
  15q24.1
• Discovery year
  2005-08-02
• Entrez gene record
  594855
• Pubmed identfication
  • 15911881
• RefSeq identity
  • NM_001030005
• VEGA ID
  OTTHUMG00000142816

Gene info

• Identity
  HGNC:7046
• Gene
  MGAT3
• Long gene name
  beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
• Synonyms gene name
  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
• Synonyms
  • GNT-III
• GenBank acession
  • D13789
• Locus
  22q13.1
• Discovery year
  1993-08-27
• Entrez gene record
  4248
• Pubmed identfication
  • 8370666
• RefSeq identity
  • NM_002409
• Classification
  • Mannosyl-glycoprotein N-acetylglucosaminyltransferases
• VEGA ID
  OTTHUMG00000030185

Gene info

• Identity
  HGNC:7064
• Gene
  MGST3
• Long gene name
  microsomal glutathione S-transferase 3
• Synonyms
  • GST-III
• Synonyms name
  • microsomal glutathione S-transferase III
  • microsomal GST-3
  • microsomal GST-III
• GenBank acession
  • AF026977
• Locus
  1q24.1
• Discovery year
  1997-10-16
• Entrez gene record
  4259
• Pubmed identfication
  • 9278457
• RefSeq identity
  • NM_004528
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000034627

Gene info

• Identity
  HGNC:30135
• Gene
  P4HA3
• Long gene name
  prolyl 4-hydroxylase subunit alpha 3
• Synonyms gene name
  • procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III
  • prolyl 4-hydroxylase, alpha polypeptide III
• Synonyms
  • C-P4Halpha(III)
• Synonyms name
  • collagen prolyl 4-hydroxylase alpha(III)
• GenBank acession
  • AY327887
• Locus
  11q13.4
• Discovery year
  2004-05-12
• Entrez gene record
  283208
• Pubmed identfication
  • 14500733
• RefSeq identity
  • NM_182904
• VEGA ID
  OTTHUMG00000165254

Gene info

• Identity
  HGNC:1506
• Gene
  CASP5
• Long gene name
  caspase 5
• Synonyms gene name
  • caspase 5, apoptosis-related cysteine protease
  • caspase 5, apoptosis-related cysteine peptidase
• Synonyms
  • ICE(rel)III
• Locus
  11q22.3
• Discovery year
  1996-09-13
• Entrez gene record
  838
• Pubmed identfication
  • 7797592
  • 9250871
• RefSeq identity
  • NM_004347
• Classification
  • Caspases
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000048073

Gene info

• Identity
  HGNC:5709
• Gene
  IGHVIII-82
• Long gene name
  immunoglobulin heavy variable (III)-82 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-82
  • immunoglobulin heavy variable (III)-82 pseudogene
• Synonyms
  • IGHV(III)-82
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28338
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151732

Gene info

• Identity
  HGNC:23187
• Gene
  THAP4
• Long gene name
  THAP domain containing 4
• Synonyms
  • CGI-36
  • Nb(III)
• Synonyms name
  • nitrobindin
• GenBank acession
  • AF258556
• Locus
  2q37.3
• Discovery year
  2003-10-08
• Entrez gene record
  51078
• Pubmed identfication
  • 12575992
  • 10810093
  • 30524950
• RefSeq identity
  • NM_015963
• Classification
  • THAP domain containing
• VEGA ID
  OTTHUMG00000133410

Gene info

• Identity
  HGNC:7426
• Gene
  MT-CSB3
• Long gene name
  mitochondrially encoded conserved sequence block III
• Synonyms gene
  • MTCSB3
• Synonyms gene name
  • conserved sequence block III
• Synonyms
  • CSB-III
• Locus
  mitochondria
• Discovery year
  1989-10-11
• Pubmed identfication
  • 2982153
• Classification
  • Mitochondrially encoded regions

Gene info

• Identity
  HGNC:5700
• Gene
  IGHVIII-44
• Long gene name
  immunoglobulin heavy variable (III)-44 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-44
  • immunoglobulin heavy variable (III)-44 pseudogene
• Synonyms
  • IGHV(III)-44
• GenBank acession
  • M99673
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28345
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152065

Gene info

• Identity
  HGNC:5707
• Gene
  IGHVIII-67-4
• Long gene name
  immunoglobulin heavy variable (III)-67-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (III)-67-4
  • immunoglobulin heavy variable (III)-67-4 pseudogene
• Synonyms
  • IGHV(III)-67-4
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28340
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151874

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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