Rabbit Monoclonal IgG Anti-ERG (TMPRSS2-ERG) [EP111]
-
Catalog numberERG002-1.0
-
PricePlease ask
-
Size1 ml
-
-
AvailabilityPlease contact us to check the availability
-
ImmunogenC-terminal synthetic peptide of human ERG
-
SpecificityHuman ERG
-
Species reactivityHuman, others not known
-
Product presentationPurified antibody with 0.2% BSA and 15 mM sodium azide as preservative
-
Product categoryPrimary Antibody
-
Antibody s raised inRabbit
-
Antibody s isotypeIgG
-
Antibody s cloneEP111
-
Product is supplied asliquid concentrate
-
Recommended concentration for use1:50 - 1:100
-
Protein concentrationN/A
-
Positive controlERG-positive prostate carcinoma
-
PretreatmentHIER (heat induced epitope retrieval)
-
Tested applicationsIHC (P)
-
Recommended secondary reagentAnti-rabbit IgG:Biotin conjugate (code no. ZU101) in conjunction with Streptavidin-HRPO (code no. ZU054) or VECTOR ImmPress rabbit IgG Kit (code no. MP-7401).
-
Storage methodStore at 2-8°C
-
Litterature1. Park K, Tomlins SA, Mudaliar KM, Chiu YL, Esgueva R, Mehra R, Suleman K, Varambally S, Brenner JC, MacDonald T, Srivastava A, Tewari AK, Sathyanarayana U, Nagy D, Pestano G, Kunju LP, Demichelis F, Chinnaiyan AM, Rubin MA. Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia. 2010 Jul;12(7):590-598. 2. Chaux,A., Albadine,R., Toubaji,A., Hicks,J., Meeker,A., Platz,E.A et al. (2011) Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas, Am. J. Surg. Pathol. 35 (7), 1014-1020 PUBMED 21677539 3. Yaskiv,O., Zhang,X., Simmerman,K., Daly,T., He,H., Falzarano,S., Chen,L., Magi-Galluzzi,C. and Zhou,M. (2011) The utility of ERG/P63 double immunohistochemical staining in the diagnosis of limited cancer in prostate needle biopsies, Am. J. Surg. Pathol. 35 (7), 1062-1068 PUBMED 21623182 4. Miettinen,M., Wang,Z.F., Paetau,A., Tan,S.H., Dobi,A., Srivastava,S. and Sesterhenn,I. (2011) ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma, Am. J. Surg. Pathol. 35 (3), 432-441 PUBMED 21317715 5. Queisser A., Hagedorn S.A., Braun M., Vogel W., Duensing S., Perner S. (2015) Comparison of different prostatic markers in lymph node and distant metastases of prostate cancer. ModernPathology 28, 138–145.
-
TipsGentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. The preservative sodium azide has been added in very small quantities. Nevertheless, it may be harmful to health and the reagent should be used only by trained personnel. For waste disposal, please refer to national regulations.
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin nameOryctolagus cuniculus
-
Gene target
-
Gene symbolERG, CUZD1, TMPRSS2
-
Short nameResearch
-
TechniqueRabbit, anti-, anti, IgG, antibody to, antibodies, IgGs, Monoclonals or monoclonal antibodies
-
HostRabbit, Rabbits
-
IsotypeIgG, IgG
-
Alternative nameERG (TMPRSS2-ERG)
-
Alternative techniquerabbit-anti, antibodies, immunoglobulins
-
Gene info
-
Identity
-
Gene
-
Long gene nameETS transcription factor ERG
-
Synonyms gene name
- v-ets avian erythroblastosis virus E26 oncogene related
- v-ets avian erythroblastosis virus E26 oncogene homolog
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ETS transcription factor family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameCUB and zona pellucida like domains 1
-
Synonyms gene name
- CUB and zona pellucida-like domains 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-11-18
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametransmembrane serine protease 2
-
Synonyms gene name
- transmembrane protease, serine 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1997-05-09
-
Pubmed identfication
-
Classification
- Scavenger receptor cysteine rich domain containing
- Type II transmembrane serine proteases
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
