CD20 Antibody

  • Catalog number
    GEN438102
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    CD20
  • Other names
    B-lymphocyte antigen CD20; B-lymphocyte antigen CD20; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1; membrane-spanning 4-domains, subfamily A, member 1; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD_antigen: CD20
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    MS4A1
  • Gene name synonims
    N/A
  • Other gene names
    MS4A1; MS4A1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; CD20
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2a, kappa
  • Clone
    B9E9
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes a protein of 33-37kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    N/A
  • Form Appearance
    N/A
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
  • Tested applications
    Flow Cytometry (FC/FACS)
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    CD20  
  • Gene symbol
    MS4A1
  • Short name
    CD20 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    Anti-CD20
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    membrane spanning 4-domains A1
  • Synonyms gene
  • Synonyms gene name
    • membrane-spanning 4-domains, subfamily A, member 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1989-05-23
  • Entrez gene record
    931
  • Pubmed identfication
  • Classification
    • Membrane spanning 4-domains
    • CD molecules
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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