TrkB (Tyrosine Kinase Receptor B, Tyrosine Receptor Kinase B, Trk B, Trk-B Tyrosine Kinase, BDNF/NT 3 Growth Factors Receptor, BDNF/NT-3 Growth Factors Receptor, Brain-derived Neurotrophic Factor Receptor, EC 2.7.10.1, GP145 TrkB, GP145-TrkB, GP95 TrkB, G

• Catalog number
  GEN608916
• Price
  Please ask
• Size
  100ug

• Also known as
  TrkB
• Other names
  trkB; BDNF/NT-3 growth factors receptor; BDNF/NT-3 growth factors receptor; trk-B; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021575; OTTHUMP00000021576; OTTHUMP00000021577; trkB tyrosine kinase; tyrosine kinase receptor B; BDNF-tropomyosine receptor kinase B; neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB
• Gene name synonims
  NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB
• Other gene names
  NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2
• Clone
  9F396
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Mouse (Mus musculus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes mouse TrkB. Does not react with mouse TrkC.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Purified
• Form Appearance
  Supplied as a lyophilized powder in PBS. Reconstitute in 500ul 40-50% glycerol, PBS.
• Concentration
  N/A
• Storage and shipping
  Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile 40-50% glycerol and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 3 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  TrkB   Tyrosine   Kinase   Receptor   Tyrosine   Receptor   Kinase   Trk   Trk-B   Tyrosine   Kinase   BDNF/NT   Growth   Factors   Receptor   BDNF/NT-3   Growth   Factors   Receptor   Brain-derived   Neurotrophic   Factor   Receptor   GP145   TrkB   GP145-TrkB   GP95   TrkB  
• Gene symbol
  BDNF, SORT1, BDNF-AS, NTF4, MIR1302-3, MIR509-3, MIR7-3
• Short name
  TrkB (Tyrosine Kinase Receptor B, Tyrosine Receptor Kinase B, Trk B, Trk-B Tyrosine Kinase, BDNF/NT 3 Growth Factors Receptor, BDNF/NT-3 Growth Factors Receptor, Brain-derived Neurotrophic Factor Receptor, EC 2 7 10 1, GP145 TrkB, GP145-TrkB, GP95 TrkB, G
• Alternative name
  Anti-TrkB (Tyrosine Kinase Receptor B, Tyrosine Receptor Kinase B, Trk B, Trk-B Tyrosine Kinase, BDNF/NT 3 Growth Factors Receptor, BDNF/NT-3 Growth Factors Receptor, Brain-derived Neurotrophic Factor Receptor, EC 2.7.10.1, GP145 TrkB, GP145-TrkB, GP95 TrkB, G
• Alternative to gene target
  brain-derived neurotrophic factor, ANON2 and BULN2, BDNF and IDBG-36817 and ENSG00000176697 and 627, growth factor activity, Extracellular, Bdnf and IDBG-195506 and ENSMUSG00000048482 and 12064, BDNF and IDBG-636102 and ENSBTAG00000008134 and 617701
• Tissue
  brain

Gene info

• Identity
  HGNC:1033
• Gene
  BDNF
• Long gene name
  brain derived neurotrophic factor
• Synonyms name
  • neurotrophin
• GenBank acession
  • AB038670
• Locus
  11p14.1
• Discovery year
  1991-01-15
• Entrez gene record
  627
• Pubmed identfication
  • 2236018
  • 1889806
  • 17942328
  • 17493809
• RefSeq identity
  • NM_170735
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000178797

Gene info

• Identity
  HGNC:11186
• Gene
  SORT1
• Long gene name
  sortilin 1
• Synonyms
  • Gp95
  • NT3
• GenBank acession
  • BC023542
• Locus
  1p13.3
• Discovery year
  1996-05-14
• Entrez gene record
  6272
• RefSeq identity
  • NM_002959
• VEGA ID
  OTTHUMG00000011999

Gene info

• Identity
  HGNC:20608
• Gene
  BDNF-AS
• Long gene name
  BDNF antisense RNA
• Synonyms gene
  • BDNFOS
• Synonyms gene name
  • BDNF opposite strand (non-protein coding)
  • BDNF antisense RNA (non-protein coding)
• Synonyms
  • BT2A
  • BT2B
  • BT2C
  • BT2D
  • NCRNA00049
  • BDNF-AS1
  • BDNFAS
• Synonyms name
  • non-protein coding RNA 49
  • BDNF antisense RNA 1 (non-protein coding)
• GenBank acession
  • AY054391
• Locus
  11p14.1
• Discovery year
  2005-02-01
• Entrez gene record
  497258
• Pubmed identfication
  • 15666411
  • 22446693
  • 28777258
• RefSeq identity
  • NR_002832
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:8024
• Gene
  NTF4
• Long gene name
  neurotrophin 4
• Synonyms gene
  • NTF5
• Synonyms gene name
  • neurotrophin 5 (neurotrophin 4/5)
• Synonyms
  • NT-4/5
  • GLC1O
• Synonyms name
  • neurotrophic factor 4
• Locus
  19q13.33
• Discovery year
  1992-10-15
• Entrez gene record
  4909
• Pubmed identfication
  • 1496419
• RefSeq identity
  • NM_006179
• Classification
  • Neurotrophins
• VEGA ID
  OTTHUMG00000191728

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

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