CLEC1 Antibody

• Catalog number
  N1092-25UG
• Price
  Please ask
• Size
  0.025mg

• Category
  Antibody
• Concentration
  0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  CLEC1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 2-5ug/ml
• Notes
  Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
• Added buffer
  1X Phosphate Buffered Saline (PBS), pH 7.4
• Intented use
  This CLEC1 antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  51267
• Purity
  This antibody was purified by Protein A method
• Description
  CLEC1 is a C-type lectin receptor and part of the ‘Dectin-1 cluster’ subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.
• Immunogen
  A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.
• Storage
  Aliquot the CLEC1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CLEC1  
• Gene symbol
  CLEC1A
• Short name
  Anti-CLEC1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to CLEC1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24355
• Gene
  CLEC1A
• Long gene name
  C-type lectin domain family 1 member A
• Synonyms gene name
  • C-type lectin domain family 1, member A
• Synonyms
  • CLEC1
  • CLEC-1
  • MGC34328
• GenBank acession
  • AY358587
• Locus
  12p13.2
• Discovery year
  2005-02-09
• Entrez gene record
  51267
• Pubmed identfication
  • 10671229
  • 11745369
• RefSeq identity
  • NM_016511
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000168504

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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