Notch3, CT (Notch Homolog 3 (Drosophila), hN3, Neurogenic Locus Notch Homolog Protein 3, CADASIL, CASIL)

• Catalog number
  MBS627318
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [Notch3]
• Products_name_syn
  [Anti -Notch3, CT (Notch Homolog 3 (Drosophila), hN3, Neurogenic Locus Notch Homolog Protein 3, CADASIL, CASIL)]
• Other_names
  [neurogenic locus notch homolog protein 3; Neurogenic locus notch homolog protein 3; neurogenic locus notch homolog protein 3; Notch homolog 3; notch 3]
• Other_gene_names
  [NOTCH3; NOTCH3; IMF2; CASIL; CADASIL; Notch 3]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human NOTCH3.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Immunohistochemistry (IHC)

• Gene target
  Notch3   Notch   Homolog   hN3   Neurogenic   Locus   Notch   Homolog   Protein   CADASIL   CASIL  
• Gene symbol
  NOTCH3
• Short name
  Notch3, CT (Notch Homolog 3 ( ), hN3, Neurogenic Locus Notch Homolog Protein 3, CADASIL, CASIL)
• Host
  Rabbit
• Isotype
  IgG
• Species
  Drosophila, Drosophila subspecies d. Megalonaster or the fruit fly is used in genetic research because of the short life cycle and the possibility of knock-out and knock-ins with Cas9 for ends-in gene targets like CRISPR.Cas9 and TALEN vectors . Drosophilas
• Alternative name
  Notch3, CT (Notch Homolog 3 (Drosophila), hN3, Neurogenic Locus Notch Homolog Protein 3, CADASIL, CASIL)

Gene info

• Identity
  HGNC:7883
• Gene
  NOTCH3
• Long gene name
  notch receptor 3
• Synonyms gene
  • CADASIL
• Synonyms gene name
  • Notch (Drosophila) homolog 3
  • Notch homolog 3 (Drosophila)
  • notch 3
• Synonyms
  • CASIL
• GenBank acession
  • U97669
• Locus
  19p13.12
• Discovery year
  1994-07-04
• Entrez gene record
  4854
• Pubmed identfication
  • 7835890
• RefSeq identity
  • NM_000435
• Classification
  • Notch receptors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000183217
• Locus Specific Databases
  • NOTCH3 - CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical
  • Global Variome shared LOVD

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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