Andrographolide, Apoptosis Inducer

  • Catalog number
    SIH-220-100MG
  • Price
    Please ask
  • Size
    100 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    5508-58-7
  • Description
    Apoptosis Inducer
  • Molecular weight
    350,45 g/mol
  • Primary research fields
    Cancer, Apoptosis
  • Other name
    (3E)-4-Hydroxy-3-{2-[(1R,4aS,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
  • Product category
    Small Molecules
  • Product type
    Inducer
  • Chemical formula
    C20H30O5
  • Origin
    Synthetic
  • Purity pourcentage
    >98%
  • Soluble in
    DMSO
  • Physical appearance
    Off-white Solid
  • Storage recommendations
    -20ÂșC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
  • PubChem number
    5318517
  • Scientific context
    Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Is has been shown to be effective against certain cancers, and is an effective purgative (1). It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement (2, 3).
  • Bibliography
    1. Chakravarti R.N., Chakravarti D. (1951) Ind. Med Gaz. 86(3): 96-7. 2. Tsai H.R., et al. (2004) Eur J Pharmacol. 498: 45-52. 3. Rajagopal S., et al. (2003) J Exp. Ther. Oncol. 3: 147-158.
  • Release date
    8-Apr-2011
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of Andrographolide (SIH-220), a Induces mitochondrial -mediated apoptosis in lymphoma cells. CAS #: 5508-58-7. Molecular Formula: C20H30O5. Molecular Weight: 350.45 g/mol. Chemical structure of Andrographolide, a Induces mitochondrial -mediated apoptosis in lymphoma cells (SIH-220). CAS # 5508-58-7. Molecular Formula: C20H30O5.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.1
  • Additional description
    This 1 is suited for programmed cell-death studies.
  • Gene target
  • Short name
    Andrographolide, Apoptosis Inducer
  • Technique
    apoptosis, apoptosis pathway
  • Alternative name
    Andrographolide, programmed cellular destruction Inducer
  • Alternative technique
    celldeath
Similar products
Filters
Contact
Chat with gentaur.com employee