Recombinant Human C-C Motif Chemokine 26/CCL26(27-94) Protein

  • Catalog number
    PKSH032194-10µg
  • Price
    Please ask
  • Size
    10µg
  • Synonym
    C-C Motif Chemokine 26; CC Chemokine IMAC; Eotaxin-3; Macrophage Inflammatory Protein 4-Alpha; MIP-4-Alpha; Small-Inducible Cytokine A26; Thymic Stroma Chemokine-1; TSC-1; CCL26; SCYA26
  • Activity
    NA
  • Sequence
    Ser27-Leu94
  • Fusion tag
    NA
  • Accession
    Q9Y258
  • Expressed Host
    E.coli
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    ＞95% as determined by reducing SDS-PAGE.
  • Endotoxin
    ＜1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
  • Mol Mass
    8.2 kDa
  • AP Mol Mass
    13 kDa
  • Formulation
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
  • Background
    Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family, which involved in immunoregulatory and inflammatory processes. CCL26 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. Eotaxin-3/CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for Eotaxin-3 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant Eotaxin-3 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, Eotaxin-3 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
  • Technical data
  • Description
    Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by Elabscience in 1.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    C-C   Motif   Chemokine   26/CCL26   27-94   Protein  
  • Gene symbol
    HSD3B7, SMC4, MYB, PCK1, SFTPC, VCX3B, MAF, RFX1, EGR4
  • Short name
    Recombinant C-C Motif Chemokine 26/CCL26(27-94) Protein
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens C-C Motif Chemokine 26/chemokine (C-C motif) ligand 26(27-94) Protein
  • Alternative technique
    rec
  • Alternative to gene target
    chemokine (C-C motif) ligand 26, IMAC and MIP-4a and MIP-4alpha and SCYA26 and TSC-1, CCL26 and IDBG-22717 and ENSG00000006606 and 10344, chemokine activity, Extracellular, Ccl26 and IDBG-203924 and ENSMUSG00000070464 and 541307, CCL16 and IDBG-630591 and ENSBTAG00000007193 and 616732
Gene info
Gene info
  • Identity
    HGNC:14013
  • Gene
    SMC4
  • Long gene name
    structural maintenance of chromosomes 4
  • Synonyms gene
  • Synonyms gene name
    • SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
    • SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
  • Synonyms
  • GenBank acession
  • Locus
    3q25.33
  • Discovery year
    2001-02-22
  • Entrez gene record
    10051
  • Pubmed identfication
  • Classification
    • Structural maintenance of chromosomes proteins
    • Condensin I subunits
    • Condensin II subunits
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000159006
Gene info
  • Identity
    HGNC:7545
  • Gene
    MYB
  • Long gene name
    MYB proto-oncogene, transcription factor
  • Synonyms gene name
    • v-myb avian myeloblastosis viral oncogene homolog
  • Synonyms
  • Locus
    6q23.3
  • Discovery year
    2001-06-22
  • Entrez gene record
    4602
  • Pubmed identfication
  • Classification
    • Myb/SANT domain containing
  • VEGA ID
    OTTHUMG00000015629
  • Locus Specific Databases
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:6776
  • Gene
    MAF
  • Long gene name
    MAF bZIP transcription factor
  • Synonyms gene name
    • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
  • Synonyms
  • Locus
    16q23.2
  • Discovery year
    1991-08-01
  • Entrez gene record
    4094
  • Pubmed identfication
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
    OTTHUMG00000137621
Gene info
Gene info
MeSH Data
  • Name
    Primary Cell Culture
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Recombinant C C Motif Chemokine 26 CCL26 27 94 Protein
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