MOUSE Anti-MOUSE IL-1 ALPHA:Azide Free Antibody
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Catalog numberGEN214543
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PricePlease ask
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Size100ug
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Also known asIL-1 ALPHA
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Other namesinterleukin-1 alpha; Interleukin-1 alpha; interleukin-1 alpha; IL-1 alpha; interleukin 1 alpha; N/A
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameIL-1 ALPHA
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Gene name synonimsN/A
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Other gene namesIl1a; Il1a; Il-1a; IL-1 alpha
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneFlo1
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Host organismMouse (Mus musculus)
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Species reactivityMouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityIL-1 ALPHA This item specifically recognises mouse interleukin-1 alpha (IL-1 alpha), a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily, secreted by activated macrophages and monocytes, which mediates a wide range of immune and inflammatory responses. _x000D__x000D_IL-1 alpha and closely related IL-1 beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a. _x000D__x000D_Clone Flo1 can be used in functional studies to neutralize the activity of 125pg/ml of recombinant mouse IL-1 alpha by 95%, as tested using mouse D10(N4)M T-helper cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceAzide Free (Purified IgG - liquid)
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ConcentrationIgG concentration 1.0mg/ml
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Storage and shippingStore the antibody should be stored at -20 degrees Celsius. only. Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applicationsELISA (EIA), Functional Assay (FA)
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DescriptionThe MOUSE Anti-MOUSE IL-1 ALPHA: Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Sodium azide NaN3 is often used to prevent antibody degradation in 0,02% W/V concentrations. MBS Monoclonals supplies azide free antibodies on request. Recently MBS Monoclonals made this MOUSE Anti-MOUSE IL-1 ALPHA: Antibody available without azide. It will stick less and is more suitable for ELISA or in vivo studies. However you need to store the @VV@ frozen and ship on dry ice.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneThe Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults. Rec. E. coli interleukin-1 for cell culture or antibody production.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolIL1A, IL1B, IL1F10, IL36B, IL36A, TUBA1B, IL19, IL17F, CCL3, TUBA1A
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Short nameMOUSE Anti-MOUSE IL-1 ALPHA: Antibody
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TechniqueAntibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
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Hostmouse
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SpeciesMouse, Mouses
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Alternative nameAnti-MOUSE ANTI MOUSE INTERLEUKIN-1 ALPHA:Azide Free
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 alpha
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 family member 10
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Synonyms gene name
- interleukin 1 family, member 10 (theta)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 beta
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 8 (eta)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 36 alpha
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Synonyms gene
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Synonyms gene name
- interleukin 1 family, member 6 (epsilon)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametubulin alpha 1b
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 19
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-03-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinterleukin 17F
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-03-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 3
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Synonyms gene
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Synonyms gene name
- small inducible cytokine A3 (homologous to mouse Mip-1a)
- chemokine (C-C motif) ligand 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-07-05
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Entrez gene record
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametubulin alpha 1a
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-01-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data