Category Proteins & Peptides
Antibody is raised in see techfile
Antibody's reacts with Human, Rat, Mouse
Antibody's suited for Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.
Protein number see ncbi
Antigen-antibody binding interaction LASS2 (Longevity Assurance Homolog 2) - Blocking Peptide
Clone not specified
Antibody come from Synthetic peptide derived from human Lass2 protein
Other description Provided as solution in phosphate buffered saline with 0.08% sodium azide.
Long description LASS2, a human homologue of the yeast longevity assurance gene LAG1 is highly expressed in liver and kidney as compared to the expression of the human LAG1 homologue LAG1Hs-1. LASS2 is located on chromosome 1q11. The LASS2 protein interacts with several membrane-associated receptors or transporters. LASS2 protein inhibits the colony formation of human hepatoma cells in vitro, which suggests that this gene may be involved in the regulation of cell growth.
Antibody's reacts with these species This antibody doesn't cross react with other species
Relevant references 1: Becker I, Wang-Eckhardt L, Yaghootfam A, Gieselmann V, Eckhardt M.Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2._x000B_Histochem Cell Biol. 2008 Feb;129(2):233-41. Epub 2007 Sep 28._x000B__x000B_2: Wang X, CarrŽ W, Saxton AM, Cogburn LA. Manipulation of thyroid status and/or GH injection alters hepatic gene expression in the juvenile chicken._x000B_Cytogenet Genome Res. 2007;117(1-4):174-88._x000B__x000B_3:Senkal CE, Ponnusamy S, Rossi MJ, Bialewski J, Sinha D, Jiang JC, Jazwinski SM, Hannun YA, Ogretmen B. Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas._x000B_Mol Cancer Ther. 2007 Feb;6(2):712-22._x000B__x000B_4: Yu Y, Lu H, Pan H, Ma JH, Ding ZJ, Li YY. Expression of LASS2 controlled by LAG1 or ADH1 promoters cannot functionally complement Lag1p._x000B_Microbiol Res. 2006;161(3):203-11. Epub 2005 Sep 22._x000B_
Application Western Blot
Warnings This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Antibody's specificity No Data Available
Test You can block the antibody by the specific target amino acid sequence of peptide.
Properties blocking peptide
Description Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.