anti-NOX1 Antibody

• Catalog number
  30-236
• Price
  Please ask
• Size
  50 ug

• Gene info
  Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. The NOH-1S currents were reversibly blocked by zinc, a known H+ channel inhibitor. The NOH-1S variant does not contain an electron transport chain and it is thought that H+ conductance is its main physiologic function, whereas NOH-1L may conduct H+ ions as part of its electron transport mechanism.
• Gene names
  NOX1, GP91-2, MOX1, NOH-1, NOH1
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NOX1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  NOX1 antibody can be used for detection of NOX1 by ELISA at 1:62500. NOX1 antibody can be used for detection of NOX1 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store NOX1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Dog
• Omim nr
  148536873
• Ncbi nr
  NP_008983
• KDa
  65 kDa, 59 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  27035
• GENE symbol
  NOX1
• Antigene name
  NADPH oxidase 1
• Source
  Homo sapiens
• Protein nr
  Q9Y5S8
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NOX1  
• Gene symbol
  NOX1
• Short name
  anti-NOX1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNOX1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  NADPH oxidase 1, NOX1 and IDBG-79287 and ENSG00000007952 and 27035, NADP binding, Cell surfaces, Nox1 and IDBG-170699 and ENSMUSG00000031257 and 237038, NOX1 and IDBG-633329 and ENSBTAG00000016761 and 521681

Gene info

• Identity
  HGNC:7889
• Gene
  NOX1
• Long gene name
  NADPH oxidase 1
• Synonyms
  • NOH1
  • NOH-1
  • MOX1
  • GP91-2
• Synonyms name
  • mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating)
  • NADPH oxidase homolog-1
  • NADPH oxidase 1 variant NOH-1L
• GenBank acession
  • AF127763
• Locus
  Xq22.1
• Discovery year
  2000-03-24
• Entrez gene record
  27035
• Pubmed identfication
  • 10485709
  • 10615049
• RefSeq identity
  • NM_007052
• VEGA ID
  OTTHUMG00000022007
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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