DYRK1A Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-11834R-A555
  • Price
    Please ask
  • Size
    100ul
  • Long name
    DYRK1A Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-DYRK1A PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    DYRK1A
  • Specificity
    This is a highly specific antibody against DYRK1A.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DYRK1A
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene which is required for neurogenesis. Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation. Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases. Dyrk family members, including Dyrk1A (dual specificity tyrosine-phosphorylation-regulated kinase 1A), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions. Localized to the nucleus and highly expressed in testis, muscle and the developing nervous system, Dyrk1A, also known as MNB or MNBH, functions to phosphorylate serine, threonine and tyrosine residues on various substrates involved in signaling pathways that regulate cell proliferation. Dyrk1A is a candidate gene for learning defects that are involved in Downs syndrome (DS), suggesting a possible role for Dyrk1A in the development of DS. Four isoforms of Dyrk1A exist due to alternative splicing events.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    Dual specicity tyrosine phosphorylation regulated kinase 1A; DYRK 1; DYRK 1A; DYRK ; DYRK1 ; DYRKA; HP 86; HP86; Minibrain Drosophila homolog; Minibrain homolog; MNB ; MNB/DYRK protein kinase antibody; MNBH; Protein kinase minibrain homolog; Serine/threonine kinase MNB; DYR1A_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 555
  • French translation
    anticorps
  • Gene target
    DYRK1A  
  • Gene symbol
    DYRK1A
  • Short name
    Anti-DYRK1A
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 555
  • Alternative name
    DYRK1A Polyclonal Antibody, ALEXA FLUOR 555
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    dual specificity tyrosine phosphorylation regulated kinase 1A
  • Synonyms gene
  • Synonyms gene name
    • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
    • dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • GenBank acession
  • Locus
  • Discovery year
    1999-01-29
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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