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Sphingosine Protein Kinase C inhibitor

Sphingosine Protein Kinase C inhibitor is available 2 times from Stressma labs

SIH-202-25MG | Sphingosine, Protein Kinase C inhibitor size: 25 mg | 175.95 USD


SIH-202-100MG | Sphingosine, Protein Kinase C inhibitor size: 100 mg | 411.30 USD

Catalog number SIH-202-100MG
Supplier stressma
Price 411.30 USD
Size 100 mg
Net weight (g) 0.1
MeSH Data
Name Sphingosine
Tree numbers
  • D02.033.100.700
  • D02.033.455.843
  • D02.092.063.700
Stock availabilitIn Stock In Stock
CAS number 123-78-4
Description Protein Kinase C inhibitor
Molecular weight 299,49 g/mol
Primary research fields Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors
Other name (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol
Product category Small Molecules
Product type Inhibitor
Chemical formula C18H37NO2
Origin Synthetic
Purity pourcentage >98%
Soluble in Soluble to 100 mM in DMSO
Physical appearance Solid
Storage recommendations -20ºC
Shipping recommendations Shipped Ambient
Safety information Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
PubChem number 5280335
Scientific context Sphingosine can be phosphorylated in vivo via two kinases which leads to the formation of a potent signaling lipid. It is a selective inhibitor of protein kinase C, but does not inhibit protein kinase A or myosin light chain kinase. It also inhibits calmodulin-dependent enzymes and is the precursor of ceramide.
Bibliography 1. Radin N. (2003) Biochem J. 371(Pt2): 243-256. 2. Carter H.E., Glick F.J., Norris W.P., Phillips G.E. (1947) J Biol Chem. 170: 285-295.
Release date 16-May-2011
PubMed number Refer to PubMed
Tested applications To be tested
Tested reactivity To be tested
Representative figure legend Chemical structure of Sphingosine (SIH-202), a Protein Kinase C inhibitor. CAS #: 123-78-4. Molecular Formula: C18H37NO2. Molecular Weight: 299.49 g/mol. Chemical structure of Sphingosine, a Protein Kinase C inhibitor (SIH-202). CAS # 123-78-4. Molecular Formula: C18H37NO2.
Warning information Non-hazardous
Country of production Canada
Total weight (kg) 0.25
Additional description Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene targetSphingosine Protein Kinase inhibitor
Short name Sphingosine, Protein Kinase C inhibitor
Alternative name Sphingosine, Protein phosphorylation catalyst C suppressor
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Sphingosine, Protein Kinase C inhibitor size: 100 mg
+32-(0)1-658-90-45 [email protected]
  • Sphingosine
  • Protein
  • Kinase
  • inhibitor
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