cGMP Antibody

• Catalog number
  3568-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  cGMP
• Target Alternative Name
  Cyclic GMP , Cyclic guanosine monophosphate
• Antibody Type
  Polyclonal
• Species Reactivities
  All species
• Immunogen Sequence
  2'O-succinyl guanosine-3',5' cyclic monophosphate
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µl succinylated cGMP affinity purified rabbit IgG in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  ELISA
• Application And Usages
  1:10-50 dilutions for nonradioactive EIA assays (10 µl/assay in an 70 µl assay reaction). The material is sufficient for performing 100-500 nonradioactive EIA assays or 6,000 radioactive assays. Detect 0.1-10 pmol/assay in a 70 µl assay reaction using nonradioactive method.
• Description
  Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  cGMP  
• Gene symbol
  PDE2A, PRKG2, PDE3A
• Short name
  cGMP Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  cGMP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8777
• Gene
  PDE2A
• Long gene name
  phosphodiesterase 2A
• Synonyms gene name
  • phosphodiesterase 2A, cGMP-stimulated
• GenBank acession
  • U67733
• Locus
  11q13.4
• Discovery year
  1997-11-10
• Entrez gene record
  5138
• Pubmed identfication
  • 9210593
• RefSeq identity
  • NM_002599
• Classification
  • Phosphodiesterases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000102045

Gene info

• Identity
  HGNC:9416
• Gene
  PRKG2
• Long gene name
  protein kinase cGMP-dependent 2
• Synonyms gene name
  • protein kinase, cGMP-dependent, type II
• Synonyms
  • cGKII
  • PRKGR2
  • PKG2
• GenBank acession
  • X94612
• Locus
  4q21.21
• Discovery year
  1997-01-09
• Entrez gene record
  5593
• Pubmed identfication
  • 7498513
• RefSeq identity
  • NM_006259
• Classification
  • AGC family kinases
• VEGA ID
  OTTHUMG00000130296

Gene info

• Identity
  HGNC:8778
• Gene
  PDE3A
• Long gene name
  phosphodiesterase 3A
• Synonyms gene name
  • phosphodiesterase 3A, cGMP-inhibited
• Synonyms
  • CGI-PDE
• Synonyms name
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase A
• Locus
  12p12.2
• Discovery year
  1994-07-29
• Entrez gene record
  5139
• Pubmed identfication
  • 1315035
  • 10679291
• Classification
  • Phosphodiesterases
• VEGA ID
  OTTHUMG00000168962

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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