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Rabbit Anti Human BIM BOD Polyclonal

Rabbit Anti Human BIM BOD Polyclonal is available 29 times from Stressmark antibodies labs

SPC-113D-ALP | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: Alkaline Phosphatase size: 100 µg | 400.51 USD

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SPC-113D-A594 | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: ATTO 594 size: 100 µg | 408.46 USD

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SPC-113D-A633 | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: ATTO 633 size: 100 µg | 408.46 USD

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SPC-113D-A680 | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: ATTO 680 size: 100 µg | 408.46 USD

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SPC-113D-A700 | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: ATTO 700 size: 100 µg | 408.46 USD

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SPC-113D-FITC | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: FITC size: 100 µg | 398.24 USD

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SPC-113D-HRP | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: HRP size: 100 µg | 393.71 USD

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SPC-113D-P594 | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: PE/ATTO 594 size: 100 µg | 416.40 USD

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SPC-113D-PCP | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: PerCP size: 100 µg | 407.32 USD

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SPC-113D-RPE | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: RPE size: 100 µg | 405.05 USD

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SPC-113D-STR | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: Streptavidin size: 100 µg | 406.19 USD

Antibody's target Human BIM/BOD
Antibody's full description Rabbit Anti-Human BIM/BOD (IN) Polyclonal
Antibody's other name BCL2 like protein 11 Antibody, Bcl2 interacting mediator of cell death Antibody, Bcl2 interacting protein Bim Antibody, BCL2 like 11 Antibody, BAM Antibody, BimEl Antibody, BimL Antibody, BOD Antibody, BIM beta 6 Antibody, BIM Beta7 Antibody, BIM alpha 3 Antibody, BIM alpha4 Antibody, BIM alpha5 Antibody, BIM alpha6 Antibody
Verified applications WB, IHC
Antibody's recommended dilutions for use WB (1:1000), IHC (1:100); optimal dilutions for assays should be determined by the user.
Certificate of analysis 1 µg/ml of SPC-113 was sufficient for detection of Bim in 20 µg of K562 and A549 cell lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Scientific context Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1 ,2).
Bibliography 1. O'Connor L., Strasser A., O'Reilly L.A., et al. (1998) EMBO J. 17: 384-395. 2. Hsu S.Y., Lin P., and Hsueh A.J. (1998) Mol. Endocrinol. 12: 1432-40.
PubMed number 27689871
Tested applications Western Blot
Tested reactivity Human
Representative figure linkmore | details
Representative figure legend Immunohistochemistry analysis using Rabbit Anti-BIM Polyclonal Antibody (SPC-113). Tissue: skin cancer cells. Species: Human. Primary Antibody: Rabbit Anti-BIM Polyclonal Antibody (SPC-113) at 1:100. | Western blot analysis of Human K562 (Left) and A549 (Right) whole cell lysates showing detection of BIM protein using Rabbit Anti-BIM Polyclonal Antibody (SPC-113). Primary Antibody: Rabbit Anti-BIM Polyclonal Antibody (SPC-113) at 1:1000. Rabbit Anti-BIM Antibody used in Immunohistochemistry (IHC) on Human skin cancer cells (SPC-113) | Rabbit Anti-BIM Antibody used in Western blot (WB) on Human K562 (Left) and A549 (Right) whole cell lysates (SPC-113)
Net weight (g) 0.1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Test StressMark antibodies supplies antibodies that are for research of human proteins.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name Oryctolagus cuniculus
Gene targetBIM/BOD Streptavidin
Short name Rabbit Anti- BIM/BOD (IN) Polyclonal: Streptavidin
Technique anti-Human, Polyclonal, Rabbit, anti
Label streptavidin
Alternative name production species: rabbit antibody to-H. sapiens BIM/BOD (IN) polyclonal: biotinilated-binding streptavidin
1. Gene info
Identity994
Long gene nameBCL2 like 11
Synonyms gene name
  • BCL2-like 11 (apoptosis facilitator)
GenBank acession
Locus2q13
Discovery year1999-12-10
Pubmed identfication
Havana BLAST/BLATOTTHUMG00000131256
Locus Specific Databases
2. Gene info
Identity1681
GeneCD44
Synonyms gene
Synonyms gene name
  • CD44 antigen (homing function and Indian blood group system)
GenBank acession
Locus11p13
Discovery year1989-06-30
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000044388
Locus Specific Databases
  • LRG_815
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Product images
    #Human#.jpg

SPC-113C | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: Unconjugated size: 25 µg | 187.21 USD

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SPC-113D | Rabbit Anti-Human BIM/BOD (IN) Polyclonal: Unconjugated size: 100 µg | 354.00 USD

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SPC-164D-ALP | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: Alkaline Phosphatase size: 100 µg | 442.49 USD

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SPC-164D-APC | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: APC size: 100 µg | 448.17 USD

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SPC-164D-A390 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: ATTO 390 size: 100 µg | 450.44 USD

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SPC-164D-A565 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: ATTO 565 size: 100 µg | 449.30 USD

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SPC-164D-A594 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: ATTO 594 size: 100 µg | 449.30 USD

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SPC-164D-A655 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: ATTO 655 size: 100 µg | 449.30 USD

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SPC-164D-A680 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: ATTO 680 size: 100 µg | 449.30 USD

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SPC-164D-A700 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: ATTO 700 size: 100 µg | 449.30 USD

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SPC-164D-BI | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: Biotin size: 100 µg | 444.76 USD

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SPC-164D-FITC | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: FITC size: 100 µg | 440.22 USD

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SPC-164D-HRP | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: HRP size: 100 µg | 435.69 USD

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SPC-164D-P594 | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: PE/ATTO 594 size: 100 µg | 457.24 USD

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SPC-164D-PCP | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: PerCP size: 100 µg | 448.17 USD

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SPC-164D-RPE | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: RPE size: 100 µg | 445.90 USD

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SPC-164C | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: Unconjugated size: 25 µg | 216.71 USD

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SPC-164D | Rabbit Anti-Human BIM/BOD (IN2) Polyclonal: Unconjugated size: 100 µg | 394.84 USD

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Recommended buffer for storage PBS, 50% glycerol, 0.09% sodium azide
Antibody's reactivity Human, Mouse, Rat
Warning information Non-hazardous
Raised in Rabbit
NCBI number NP_619527.1
Gene number 10018
Released date 1/Jun/2007
Immunogen Internal central amino acids of human Bim
Protein number O43521
Primary research fields Cancer, Apoptosis
Antibody's datasheet Contact our support service to receive datasheet or other technical documentation.
Total weight (kg) 1.4
Stock availabilit In Stock
Tissue specificity See included datasheet or contact our support service.
Country of production Canada
Antibody's purified from Protein A Purified
Antibody's concentration 1 mg/ml
Antibody in cell Mitochondrion, Endomembrane System
Antibody's category Polyclonal Antibodies
Antibody's specificity Detects ~23kDa.
Storage recommendations -20°C
Shipping recommendations Blue Ice or 4°C
Host Rabbit
Species Human
Alternative technique polyclonals
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