CD108 / Semaphorin 7a monoclonal antibody

• Catalog number
  1F-275-T100
• Price
  Please ask
• Size
  100 assays

• Long name
  Mouse Monoclonal Antibody against Human CD108 / Semaphorin 7a, Clone: MEM-150
• Antigen
  CD108
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-150
• Applications
  FC, IP, WB
• Immunogen
  HPB-ALL human T cell line
• Format conjugation
  FITC
• Specificity
  The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes._x000D_ HLDA V; WS Code AS S017_x000D_ HLDA V; WS Code BP BP347 _x000D_ HLDA VI; WS Code BP 401 _x000D_ HLDA VI; WS Code BP 475 _x000D_ HLDA VI; WS Code NL N-L156 _x000D_ HLDA VI; WS Code P PR-65 _x000D_
• Research area
  Blood Group Antigens (Human), CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing Tris buffered saline (TBS) solution containing 15 mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD108 / Semaphorin 7a, Clone: MEM-150 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors – plexin C1 and beta1 integrins.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  *Mudad R, Rao N, Angelisova P, Horejsi V, Telen MJ.: Evidence that CDw108 membrane protein bears the JMH blood group antigen. Transfusion. 1995 Jul;35(7):566-70. _x000D_ , *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997)., *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995)., *Angelisova P, Drbal K, Cerny J, Hilgert I, Horejsi V: Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules. Immunobiology. 1999 Jun;200(2):234-45. _x000D_
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD108   Semaphorin   monoclonal  
• Gene symbol
  SEMA7A
• Short name
  Anti-CD108 / Semaphorin 7a Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgM
• Alternative name
  Mouse Monoclonal to CD108 / Semaphorin 7a
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10741
• Gene
  SEMA7A
• Long gene name
  semaphorin 7A (John Milton Hagen blood group)
• Synonyms gene
  • SEMAL
• Synonyms gene name
  • sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
  • sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)
  • semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
• Synonyms
  • H-Sema-L
  • CD108
• Synonyms name
  • John Milton Hagen blood group
  • H-Sema K1
• GenBank acession
  • AF069493
• Locus
  15q24.1
• Discovery year
  1999-06-25
• Entrez gene record
  8482
• Pubmed identfication
  • 9721204
• RefSeq identity
  • NM_003612
• Classification
  • Immunoglobulin like domain containing
  • Semaphorins
  • MicroRNA protein coding host genes
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000139000
• Locus Specific Databases
  • LRG_818

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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