CPB2 Antibody, Cy5.5 Conjugated

• Catalog number
  bs-7547R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  CPB2 Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CPB2
• Specificity
  This is a highly specific antibody against CPB2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human CPB2
• Gene ID number
  1361
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues; pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 ug/ml. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  Carboxypeptidase B like protein; Carboxypeptidase U; CarboxypeptidaseB2; Carboxypeptidase B2; CarboxypeptidaseU; CP B2; CPB 2; CPB2; CPU; PCPB; Plasma carboxypeptidase B; Plasma carboxypeptidase B2; Procarboxypeptidase B; Procarboxypeptidase R; Procarboxypeptidase U; TAFI; Thrombin activable fibrinolysis inhibitor; Thrombin activatable fibrinolysis inhibitor.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  CPB2   Conjugated  
• Gene symbol
  CPB2-AS1, CPB2
• Short name
  Anti-CPB2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-CPB2 PAb Cy5.5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:39898
• Gene
  CPB2-AS1
• Long gene name
  CPB2 antisense RNA 1
• Synonyms gene name
  • CPB2 antisense RNA 1 (non-protein coding)
• Locus
  13q14.13
• Discovery year
  2011-04-08
• Entrez gene record
  100509894
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000016865

Gene info

• Identity
  HGNC:2300
• Gene
  CPB2
• Long gene name
  carboxypeptidase B2
• Synonyms gene name
  • carboxypeptidase B2 (plasma, carboxypeptidase U)
  • carboxypeptidase B2 (plasma)
• Synonyms
  • CPU
  • PCPB
  • TAFI
• Synonyms name
  • thrombin-activatable fibrinolysis inhibitor
  • carboxypeptidase U
  • plasma carboxypeptidase B
  • carboxypeptidase R
• GenBank acession
  • M75106
• Locus
  13q14.13
• Discovery year
  1992-04-10
• Entrez gene record
  1361
• Pubmed identfication
  • 1939207
  • 1427879
• RefSeq identity
  • NM_001872
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000016867
• Locus Specific Databases
  • LRG_632

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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