JMJD6 Antibody

• Catalog number
  6109-50
• Price
  Please ask
• Size
  50 μg

• Antibody Target
  JMJD6
• Target Alternative Name
  Jumonji Domain Containing 6; PTDSR
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, chimpanzee, bovine, canine, equine, mouse, opossum
• Immunogen Sequence
  Human recombinant JMJD2A aa 127-144
• Accession
  Q6NYC1
• Gene Id
  23210
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  50 µg of antibody in 100 µl PBS containing 0.05% BSA and 0.05% sodium salt.
• Purification
  Antigen affinity purified
• Application
  Western blot
• Positive Control
  Western blot: Human brain lysate, mouse brain lysate
• Application And Usages
  Western blot: 0.25-1.0 µg/ml. However, the optimal conditions should be determined individually.
• Description
  Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. JMJD6 is a 403 amino acid nuclear protein lysyl-hydroxylase that has been reported to have arginine demethylase activity for histone H3 at ‘Arg-2’ and histone H4 at ‘Arg-3’. JMJD6 has been sμggested to function in the differentiation of multiple organs during embryogenesis and regulate hematopoietic differentiation and macrophage cytokine responses. First identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, JMJD6 was later indicated not to directly function in the clearance of apoptotic cells. It is ubiquitously expressed in most tissues and is upregulated in patients with chronic pancreatitis and upon cytokine treatment, but not upon TNF-α treatment.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  JMJD6  
• Gene symbol
  JMJD6
• Short name
  JMJD6 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  jumonji domain containing 6 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  jumonji domain containing 6, PSR and PTDSR and PTDSR1, JMJD6 and IDBG-70010 and ENSG00000070495 and 23210, peptidyl-lysine 5-dioxygenase activity, nuclei, Jmjd6 and IDBG-214522 and ENSMUSG00000056962 and 107817, JMJD6 and IDBG-643020 and ENSBTAG00000019153 and 508343

Gene info

• Identity
  HGNC:19355
• Gene
  JMJD6
• Long gene name
  jumonji domain containing 6, arginine demethylase and lysine hydroxylase
• Synonyms gene
  • PTDSR
• Synonyms gene name
  • phosphatidylserine receptor
  • jumonji domain containing 6
• Synonyms
  • PTDSR1
  • KIAA0585
• GenBank acession
  • AB011157
• Locus
  17q25.1
• Discovery year
  2002-10-09
• Entrez gene record
  23210
• Pubmed identfication
  • 11877474
• RefSeq identity
  • NM_015167
• Classification
  • Iron (II) and 2-oxoglutarate dependent oxygenases
• VEGA ID
  OTTHUMG00000169267

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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