L3MBTL1 polyclonal antibody
-
Catalog number
6857-25
-
Price
Please ask
-
Size
25 μg
-
-
Antibody Target
L3MBTL1
-
Target Alternative Name
L3MBTL, L3MBT
-
Antibody Type
Polyclonal
-
Species Reactivities
Human.
-
Immunogen Sequence
Polyclonal antibody raised in rabbit against human L3MBTL1 (lethal 3 malignant brain tumor-like protein), using the N-terminal part of the protein.
-
Accession
Q9Y468
-
Gene Id
26013
-
Appearance
Colorless liquid
-
Form
Liquid
-
Formulation
In PBS with 0.05% sodium azide and 0.05% ProClin 300.
-
Purification
Protein G purified
-
Application
Western blot, IP.
-
Positive Control
Western blot: HeLa cells, IP: HeLa cells
-
Application And Usages
Western Blot: 1:1000, IP: 1 - 5 µg/IP
-
Description
L3MBTL1 is a member of the polycomb group (PcG) proteins, which function as transcriptional regulators in large protein complexes. In Drosophila, homozygous mutations in the L3MBTL1 gene have been demonstrated to cause brain tumors, identifying L3MBTL1 as a tumor suppressor gene. L3MBTL1 forms a homodimer and interacts with TEL (ETV6). L3MBTL1 probably plays a role in cell proliferation. Overexpression of L3MBTL1 induces multinucleated cells, suggesting that it is required for normal mitosis.
-
Storage Condition
-20 °C
-
Shipping Condition
gel pack
-
Shelf Life
12 months
-
Usage
For Research Use Only! Not to be used in humans.
-
Handling
The antibody solution should be gently mixed before use.
-
Western Blot Verified
Verified
-
Immunocytochemistry Verified
Not Verified
-
Immunofluorescence Verified
Not Verified
-
Immunoprecipitation Verified
Verified
-
ELISA Verified
Not Verified
-
ChIP Verified
Not Verified
-
Dot Blot Verified
Not Verified
-
Flow Cytometry Verified
Not Verified
-
-
Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Group
Polyclonals and antibodies
-
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
French translation
anticorps
-
Gene target
-
Gene symbol
L3MBTL1
-
Short name
L3MBTL1 polyclonal antibody
-
Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
Isotype
Rabbit IgG
-
Alternative name
l(3)mbt-like 1 (Drosophila) polyclonal (antibody to-)
-
Alternative technique
polyclonals, antibodies
-
Alternative to gene target
l(3)mbt-like 1 (Drosophila), dJ138B7.3 and H-L(3)MBT and L3MBTL and ZC2HC3, L3MBTL1 and IDBG-75814 and ENSG00000185513 and 26013, identical protein binding, nuclei, L3mbtl1 and IDBG-211789 and ENSMUSG00000035576 and 241764
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
