Human Transcription factor SOX-2 (SOX2)

  • Catalog number
    CSB-EP1653HU-1MG
  • Price
    Please ask
  • Size
    1MG
  • Description
    Recombinant Human Transcription factor SOX-2(SOX2) expressed in E.coli
  • Specifications
    Uniprot ID: P48431; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-317aa; Sequence information: Full Length; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
  • Additional_information
    MW: 50.3 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
  • Storage_and_shipping
    Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
  • Notes
    For research use only.
  • Additional description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Gene target
  • Gene symbol
    SOX2, SOX2-OT, SOX13, SOX10, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2
  • Short name
    Transcription factor SOX-2 (SOX2)
  • Species
    Human, Humans
  • Alternative name
    H. sapiens Transcription factor SOX-2 (SRY (sex determining region Y)-box 2)
  • Alternative to gene target
    SRY (sex determining region Y)-box 2, ANOP3 and MCOPS3, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, protein heterodimerization activity, nuclei, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383
Gene info
  • Identity
  • Gene
  • Long gene name
    SRY-box transcription factor 2
  • Synonyms gene name
    • SRY (sex determining region Y)-box 2
    • SRY-box 2
  • GenBank acession
  • Locus
  • Discovery year
    1993-11-30
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • SRY-box transcription factors
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
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Gene info
Gene info
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