Human Transcription factor SOX-2 (SOX2)
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Catalog numberCSB-EP022426HU-10ug
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PricePlease ask
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Size10ug
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DescriptionRecombinant Human Transcription factor SOX-2(SOX2) expressed in E.coli
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SpecificationsUniprot ID: P48431; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-317aa; Sequence information: Full Length; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
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Additional_informationMW: 50.3 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
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Storage_and_shippingShipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
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NotesFor research use only.
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Additional descriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolSOX2, SOX2-OT, SOX13, SOX10, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2
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Short nameTranscription factor SOX-2 (SOX2)
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SpeciesHuman, Humans
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Alternative nameH. sapiens Transcription factor SOX-2 (SRY (sex determining region Y)-box 2)
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Alternative to gene targetSRY (sex determining region Y)-box 2, ANOP3 and MCOPS3, SOX2 and IDBG-66692 and ENSG00000181449 and 6657, protein heterodimerization activity, nuclei, Sox2 and IDBG-137912 and ENSMUSG00000074637 and 20674, SOX2 and IDBG-647279 and ENSBTAG00000011598 and 784383
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Gene info
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Identity
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Gene
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Long gene nameSRY-box transcription factor 2
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Synonyms gene name
- SRY (sex determining region Y)-box 2
- SRY-box 2
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GenBank acession
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Locus
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Discovery year1993-11-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SRY-box transcription factors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameSOX2 overlapping transcript
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Synonyms gene
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Synonyms gene name
- SOX2 overlapping transcript (non-protein coding)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-07-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Overlapping transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSRY-box transcription factor 13
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Synonyms gene name
- SRY (sex determining region Y)-box 13
- SRY-box 13
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Synonyms
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Synonyms name
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Locus
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Discovery year1998-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SRY-box transcription factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSRY-box transcription factor 10
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Synonyms gene name
- SRY (sex determining region Y)-box 10
- SRY-box 10
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Synonyms
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Synonyms name
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Locus
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Discovery year1998-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SRY-box transcription factors
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 329-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-11
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR329 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family