Elafin Antibody

• Catalog number
  R32376
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Elafin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, ELISA
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (FFPE): 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml
• Notes
  Optimal dilution of the Elafin antibody should be determined by the researcher.
• Intented use
  This Elafin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P19957
• Purity
  Antigen affinity
• Description
  Elafin, also known as peptidase inhibitor 3 or skin-derived antileukoprotease (SKALP), is a protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. And this gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
• Immunogen
  Amino acids A61-Q117 from the human protein were used as the immunogen for the Elafin antibody.
• Storage
  After reconstitution, the Elafin antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Cytoplasmic
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Elafin  
• Gene symbol
  PI3
• Short name
  Anti-Elafin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Elafin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8947
• Gene
  PI3
• Long gene name
  peptidase inhibitor 3
• Synonyms gene name
  • protease inhibitor 3, skin-derived (SKALP)
  • peptidase inhibitor 3, skin-derived
• Synonyms
  • ESI
  • SKALP
  • ELAFIN
  • WAP3
  • WFDC14
  • cementoin
• Synonyms name
  • skin-derived antileukoproteinase
  • trappin-2
• GenBank acession
  • D13156
• Locus
  20q13.12
• Discovery year
  1993-07-27
• Entrez gene record
  5266
• Pubmed identfication
  • 8287685
  • 12206714
• RefSeq identity
  • NM_002638
• Classification
  • WAP four-disulfide core domain containing
• VEGA ID
  OTTHUMG00000032567

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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