GRO-alpha/MGSA, human recombinant

• Catalog number
  4104-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Growth Regulated Protein/Melanoma Growth Stimulatory Activity, GRO α, MGSA α, CXCL1, NAP-3, GRO1, KC (murine) CINC (rat)
• Alternative_names
  Growth Regulated Protein/Melanoma Growth Stimulatory Activity, GRO α, MGSA α, CXCL1, NAP-3, GRO1, KC (murine) CINC (rat), Neutrophil-activating protein 3
• Description
  A cytokine with mitogenic properties
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Purity
  ≥98%
• Biological activity
  Determined by its ability to chemoattract human neutrophils using a concentration range of 10-50 ng/ml.
• Results
  10-50 ng/ml.
• Molecular Weight
  7.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Lyophilized with no additives
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
• Background Information
  Human GRO/MGSA (also known as GRO α) promotes neutrophil chemotaxis and degranulation. It also stimulates mutagenesis in certain human melanoma cells. Recombinant human GRO/MGSA is a 7.8 kDa protein containing 73 amino acid residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional description
  The GRO-alpha/MGSA, recombinant is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  GRO-alpha/MGSA  
• Gene symbol
  CXCL1, CXCL2
• Short name
  GRO-alpha/MGSA, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  GRO-a/MGSA, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:4602
• Gene
  CXCL1
• Long gene name
  C-X-C motif chemokine ligand 1
• Synonyms gene
  • MGSA
  • GRO1
  • FSP
• Synonyms gene name
  • GRO1 oncogene (melanoma growth stimulating activity, alpha)
  • fibroblast secretory protein
  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
• Synonyms
  • SCYB1
  • GROa
  • MGSA-a
  • NAP-3
• Synonyms name
  • melanoma growth stimulating activity, alpha
• GenBank acession
  • J03561
• Locus
  4q13.3
• Discovery year
  1988-08-11
• Entrez gene record
  2919
• Pubmed identfication
  • 2217207
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000160866

Gene info

• Identity
  HGNC:4603
• Gene
  CXCL2
• Long gene name
  C-X-C motif chemokine ligand 2
• Synonyms gene
  • GRO2
• Synonyms gene name
  • GRO2 oncogene
  • chemokine (C-X-C motif) ligand 2
• Synonyms
  • SCYB2
  • GROb
  • MIP-2a
  • MGSA-b
  • CINC-2a
• GenBank acession
  • M36820
• Locus
  4q13.3
• Discovery year
  1991-05-21
• Entrez gene record
  2920
• Pubmed identfication
  • 2217207
• RefSeq identity
  • NM_002089
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000160865

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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